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[Clinical study on cefprozil in pediatrics].

Author: IwaiN, KasaiK, MiyazuM, NakamuraH

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Overview

Cefprozil (CFPZ) demonstrated excellent clinical efficacy and a high bacteriological eradication rate in treating pediatric infections, particularly against Gram-positive bacteria. No significant side effects were observed, except for elevated eosinophil counts in 3 patients.
Paper Details　
Original Abstract of the Article :
Clinical efficacy and safety of cefprozil (CFPZ, BMY-28100), a newly developed oral cephalosporin, were studied in our pediatric department. Clinical effectiveness, bacteriological effectiveness and side effects were studied in 116 pediatric patients with ages ranging 4 months to 11 years. CFPZ was ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1494236

データ提供：米国国立医学図書館（NLM）

Cefprozil: A Promising Treatment for Pediatric Infections

Infections in children can be particularly challenging to manage due to their developing immune systems. This study explores the efficacy and safety of cefprozil, a newly developed oral cephalosporin antibiotic, in treating infections in pediatric patients. The study involved 116 children ranging in age from 4 months to 11 years, with various infections, including pharyngitis, tonsillitis, bronchitis, pneumonia, and urinary tract infections. Cefprozil was administered at a dose of 4.6 to 14.1 mg/kg per day, divided into three doses, for a duration of 3 to 10 days. The researchers evaluated both clinical and bacteriological responses to treatment. Their findings indicate that cefprozil is a safe and highly effective antibiotic for treating infections in pediatric patients.

Cefprozil: A Safe and Effective Antibiotic for Children

The study revealed that cefprozil demonstrated excellent or good clinical effectiveness in treating various infections in the pediatric population. The overall effectiveness rate was 96.4%. Cefprozil was particularly effective against Gram-positive bacteria, achieving a bacteriological eradication rate of 97.1%.

Navigating Pediatric Infections: A Vital Tool for Clinicians

This research highlights the value of cefprozil as a safe and effective treatment option for infections in pediatric patients. It provides clinicians with a valuable tool for managing a range of infections in this vulnerable population.

Dr. Camel's Conclusion

Treating infections in children can feel like traversing a vast desert of uncertainty, filled with the potential for complications. This study offers a beacon of hope, highlighting the efficacy and safety of cefprozil in battling these infections. It provides clinicians with a powerful tool for protecting children's health and ensuring their well-being. Let's continue to explore new avenues for treating pediatric infections, ensuring that these young travelers can navigate the desert safely and thrive.

Date :
  1. Date Completed 1993-03-11
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

1494236

DOI: Digital Object Identifier

1494236

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Languages

Japanese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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