Two doses of oral sustained-release tramadol do not reduce pain or morphine consumption after modified radical mastectomy: a randomized, double blind, placebo-controlled trial.

Author: KlaichanadChongsuk, KrisanaprakornkitWimonrat, TaesiriWorranut, ThaninsuratNuanchan, ThienthongSomboon, UtsahapanichSiriporn

Paper Details 
Original Abstract of the Article :
Tramadol is a weak opioid agonist with antinociceptive effects through its action on the mu-receptor and by inhibiting the neuronal re-uptake of both noradrenaline and serotonin. Tramadol is commonly used for treatment of mild to moderate post-operative pain. An oral form of sustained-release tramad...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/14971531

データ提供:米国国立医学図書館(NLM)

A Quest for Pain Relief: Tramadol's Journey in Modified Radical Mastectomy

The quest for pain relief after surgery is a constant challenge, much like navigating a treacherous desert. This study examines the effectiveness of tramadol, a weak opioid agonist, in managing post-operative pain following modified radical mastectomy, a procedure commonly used to treat breast cancer. The authors conducted a double-blind, placebo-controlled trial, comparing the effects of two doses of sustained-release tramadol (SR) to placebo. The results of their journey through the desert of pain relief are revealing: despite tramadol's potential, the study did not find a significant reduction in pain or morphine consumption in the treatment group. This study underscores the need for further exploration of pain management strategies following breast cancer surgery, seeking alternative pathways to provide effective relief for those navigating this difficult terrain.

The Search for a Pain-Free Oasis

The study's findings highlight the complex nature of post-operative pain management, emphasizing the need for continued research into alternative approaches. It's like searching for an elusive oasis in a vast desert, requiring persistence and a willingness to explore new possibilities. Further exploration of different medications and pain management techniques is crucial to provide effective relief for those seeking solace from the desert of post-operative pain.

Navigating the Desert of Pain

As a desert wanderer, I've experienced the harshness of pain and the relentless pursuit of relief. This study resonates with me, emphasizing the ongoing challenge of providing effective pain management for those facing difficult medical journeys. It's like searching for a cool spring in a barren desert, a quest that requires dedication and innovation.

Dr. Camel's Conclusion

This study explores the use of tramadol in managing post-operative pain after modified radical mastectomy. While the results do not show significant pain relief, the research highlights the need for further exploration of effective pain management strategies, emphasizing the importance of finding a path towards a pain-free oasis for those navigating this challenging terrain.
Date :
  1. Date Completed 2004-03-12
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

14971531

DOI: Digital Object Identifier

14971531

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English

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