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Subjective effects of slow-release bupropion versus caffeine as determined in a quasi-naturalistic setting.

Author: BergerIris, De WitHarriet, KemmlerGeorg, NienhusmeierMatthias, SariaAlois, SturmKatja, TelserStefan, WakoniggGudrun, ZernigGerald

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Bupropion is a drug used for smoking cessation. This study examined its potential for abuse liability in smokers. Bupropion produced subjective effects indicative of abuse liability in a small subgroup of smokers.
Paper Details　
Original Abstract of the Article :
Bupropion (BUP), which in its slow-release formulation (Zyban) is used as a smoking-cessation drug, increases dopamine overflow in the nucleus accumbens and serves as a reinforcer in animal experiments, both suggesting that BUP may possess some abuse liability. The present study examined if BUP prod...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/15001822

データ提供：米国国立医学図書館（NLM）

Bupropion and Caffeine: Exploring the Landscape of Subjective Effects

Bupropion, a medication used for smoking cessation, has been shown to have reinforcing effects in animal studies. This study investigates the subjective effects of bupropion, compared to caffeine, in a quasi-naturalistic setting, exploring potential for abuse liability. Think of it like mapping a desert landscape: understanding the different effects of various substances can provide valuable insights.

Bupropion and Caffeine: A Comparison of Subjective Effects

This research provides a comparison of the subjective effects of bupropion and caffeine, highlighting potential differences in their impact on mood and behavior. It's like comparing two different desert oases: each offers unique characteristics and experiences. The study reveals that both bupropion and caffeine can produce subjective effects, but the nature and extent of these effects vary.

Understanding the Potential for Abuse: Navigating the Desert of Addiction

This research highlights the importance of understanding the potential for abuse of medications like bupropion. It's like recognizing the dangers of mirages in the desert: knowing the potential pitfalls can help individuals make informed decisions about medication use. The study underscores the need for careful monitoring and responsible prescribing of medications with potential for abuse.

Dr.Camel's Conclusion

This study provides valuable insights into the subjective effects of bupropion and caffeine, highlighting the potential for abuse liability. It underscores the importance of understanding the complex interplay of factors that can contribute to drug use and the need for responsible prescribing practices to minimize the risks of misuse.

Date :
  1. Date Completed 2004-07-14
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

15001822

DOI: Digital Object Identifier

75550

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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