Olanzapine plasma concentration, average daily dose, and interaction with co-medication in schizophrenic patients.

Author: BergemannN, FrickA, KopitzJ, ParzerP

Paper Details 
Original Abstract of the Article :
Olanzapine, a thienobenzodiazepine, is one of the relatively new atypical antipsychotic drugs. The lowest threshold of effective olanzapine plasma levels in inpatient treatment is assumed to be 9 ng/ml. Very little is known about the plasma concentration in patients at various oral doses of olanzapi...See full text at original site
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引用元:
https://doi.org/10.1055/s-2004-815527

データ提供:米国国立医学図書館(NLM)

Examining Olanzapine Plasma Concentrations and Interactions

The field of [atypical antipsychotic drugs] is constantly evolving, and researchers are dedicated to understanding the intricacies of these medications. This study focuses on [olanzapine], a thienobenzodiazepine that has emerged as a promising treatment option for [schizophrenia]. The researchers aim to shed light on the [relationship between olanzapine plasma concentration, dosage, and interactions with co-medications]. They also explored the [minimum effective plasma level] of olanzapine, which is believed to be [9 ng/ml] for inpatient treatment.

Understanding the Role of Olanzapine Dosage

This research delves into the complex world of [pharmacokinetics] and its impact on the effectiveness of olanzapine. The study provides valuable information about the [plasma concentration of olanzapine] at various oral doses. It's like deciphering the secrets of a hidden oasis in the desert - each dose of olanzapine has its own unique effect on the body.

Managing Interactions and Optimizing Treatment

The study emphasizes the importance of considering [potential interactions] between olanzapine and co-medications. This knowledge is crucial for [optimizing treatment outcomes] and ensuring patient safety. It's like navigating the desert with a trusted guide, where knowledge of the terrain and potential hazards is essential for a successful journey.

Dr.Camel's Conclusion

This study is a step towards optimizing the use of [olanzapine] for individuals with schizophrenia. It offers valuable insights into the [pharmacokinetic profile] of olanzapine and highlights the importance of considering [potential drug interactions] in treatment planning.

Date :
  1. Date Completed 2004-08-02
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

15048613

DOI: Digital Object Identifier

10.1055/s-2004-815527

Related Literature

SNS
PICO Info
in preparation
Languages

English

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