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The Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) project: an open-label pragmatic randomised control trial comparing the efficacy of differing therapeutic agents for primary care detoxification from either street heroin or methadone [ISRCTN07752728].

Author: AdamsClive E, OldhamNicola S, SheardLaura, TompkinsCharlotte N E, WrightNat M J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study aims to compare the effectiveness of dihydrocodeine and sublingual buprenorphine in helping heroin users successfully and comfortably withdraw from heroin in a primary care setting.
Paper Details　
Original Abstract of the Article :
Heroin is a synthetic opioid with an extensive illicit market leading to large numbers of people becoming addicted. Heroin users often present to community treatment services requesting detoxification and in the UK various agents are used to control symptoms of withdrawal. Dissatisfaction with metha...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC450295/

データ提供：米国国立医学図書館（NLM）

Heroin Detoxification: A Randomized Trial Comparing Dihydrocodeine and Buprenorphine

This research explores the effectiveness of different therapeutic agents for primary care detoxification from heroin or methadone. The authors conducted a randomized controlled trial comparing dihydrocodeine and buprenorphine, two commonly used medications in the United Kingdom. This research, like a well-traveled caravan route through the desert, sheds light on the effectiveness of different treatment options for individuals seeking to overcome heroin addiction.

A Comparison of Detoxification Strategies

The study provides valuable insights into the comparative effectiveness of dihydrocodeine and buprenorphine for heroin detoxification. The authors compared the success rates and patient comfort levels associated with each medication, offering a more informed approach to treatment. This is like finding a hidden oasis in the desert of addiction treatment, providing a more tailored and effective approach to care.

Improving Detoxification Outcomes

The findings of this research have implications for improving detoxification outcomes and patient experiences. The authors highlight the importance of using evidence-based practices and choosing the most appropriate medication for individual patients. This is like selecting the safest and most efficient route through a desert landscape, ensuring a smoother and more successful journey toward recovery.

Dr. Camel's Conclusion

This research is a beacon of hope in the desert of heroin addiction, offering a more informed approach to detoxification. By comparing the effectiveness of different therapeutic agents, the authors provide valuable insights to guide clinical decision-making and improve outcomes for individuals seeking to overcome this challenging addiction. The desert of addiction treatment is vast and complex, but with continued research and a compassionate approach, we can find pathways toward recovery and healing.
Date :
  1. Date Completed 2004-07-13
  2. Date Revised 2020-12-08
Further Info :

Pubmed ID

15117415

DOI: Digital Object Identifier

PMC450295

Related Literature

Article Analysis
・Effective treatment of heroin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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