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[Pharmacological and pharmacokinetic features and clinical effects of pitavastatin (Livalo Tablet)].

Author: FujinoHideki, KanazawaMizuho, KitaharaMasaki, SatoFumiyasu, SuzukiMikio, TamakiTaro, YamazakiHiroyuki

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Pitavastatin is a medication used to lower cholesterol levels. This study reviewed the development and effectiveness of pitavastatin.
Paper Details　
Original Abstract of the Article :
Today 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) are the most often prescribed drugs among the therapeutics for hypercholesterolemia. Pitavastatin is a novel statin that has been developed entirely in Japan from the biological screening to clinical studies persuin...See full text at original site
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引用元：
https://doi.org/10.1254/fpj.123.349

データ提供：米国国立医学図書館（NLM）

Pitavastatin: A Novel Statin for Hypercholesterolemia

This research delves into the world of statins, a class of medications widely used to lower cholesterol levels. It introduces pitavastatin, a novel statin that has shown promising results in preclinical and clinical studies. The researchers highlight pitavastatin's unique properties, including its selective distribution to the liver, prolonged plasma half-life, and minimal drug interactions.

Pitavastatin: A Potential Game-Changer for Cholesterol Management

Pitavastatin demonstrated significant efficacy in lowering cholesterol levels in clinical trials, showing a reduction of 28% in total cholesterol and 40% in LDL cholesterol. This suggests that pitavastatin could be a valuable addition to the arsenal of medications available for managing hypercholesterolemia.

Promoting Cardiovascular Health

This research underscores the importance of managing cholesterol levels for cardiovascular health. Pitavastatin's potential as a safe and effective cholesterol-lowering medication offers hope for improving cardiovascular outcomes.

Dr. Camel's Conclusion

This study provides valuable insights into the potential of pitavastatin as a promising new statin for the management of hypercholesterolemia. The researchers' findings highlight the ongoing efforts to develop innovative treatments for cardiovascular disease and improve the health and well-being of individuals at risk.

Date :
  1. Date Completed 2004-07-30
  2. Date Revised 2019-09-01
Further Info :

Pubmed ID

15118259

DOI: Digital Object Identifier

10.1254/fpj.123.349

SNS
PICO Info
in preparation
Languages

Japanese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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