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Long-term effects of immunization with recombinant lipoprotein outer surface protein a on serologic test for lyme disease.

Author: FawcettPaul T, MaduskuieVictoria, RoseCarlos D

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Immunization with recombinant lipoprotein outer surface protein A vaccine is known to interfere with some serologic tests for Lyme disease. This study tested sera from 152 vaccine recipients and found that vaccination caused interference in up to 25% of recipients and can persist for over 6 years.
Paper Details　
Original Abstract of the Article :
Immunization with recombinant lipoprotein outer surface protein A vaccine is known to interfere with some serologic tests for Lyme disease. We tested sera from 152 vaccine recipients by using in-house and commercial Western blot assays and found that vaccination caused interference in up to 25% of r...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC440630/

データ提供：米国国立医学図書館（NLM）

Lyme Disease Vaccination and Serological Testing: A Complex Interaction

Lyme disease, a tick-borne illness, can be challenging to diagnose. This research explores the impact of Lyme disease vaccination on serological tests, which are commonly used to detect the disease. The study highlights the potential for interference caused by vaccination, which can complicate the interpretation of test results.

The Shifting Sands: Vaccine Interference in Lyme Disease Testing

The study found that vaccination with recombinant lipoprotein outer surface protein A vaccine can interfere with serological tests for Lyme disease in a significant proportion of recipients. This interference can persist for several years, making it crucial for healthcare providers to be aware of this potential issue when interpreting test results.

Navigating the Desert of Diagnosis: Understanding Vaccine Interference

This research underscores the need for careful consideration of vaccination history when interpreting serological tests for Lyme disease. It's like navigating a desert: we need to understand the potential pitfalls and be prepared to adjust our course accordingly.

Dr.Camel's Conclusion

This research emphasizes the importance of understanding the potential for vaccine interference in serological testing for Lyme disease. Healthcare providers should be aware of this issue and consider it when interpreting test results. It's like navigating a desert: awareness of the potential challenges is crucial for making informed decisions and ensuring accurate diagnoses.

Date :
  1. Date Completed 2005-01-13
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

15242965

DOI: Digital Object Identifier

PMC440630

Related Literature

Article Analysis
・Effective treatment of lyme disease
SNS
PICO Info
in preparation
Languages

English

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