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Retardation of joint damage in patients with early rheumatoid arthritis by initial aggressive treatment with disease-modifying antirheumatic drugs: five-year experience from the FIN-RACo study.

Author: , BlåfieldHarri, HakalaMarkku, HannonenPekka, KautiainenHannu, KorpelaMarkku, LaasonenLeena, Leirisalo-RepoMarjatta, MöttönenTimo, PaimelaLeena, PuolakkaKari

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
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Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study evaluated the long-term effectiveness of combination DMARD therapy versus single DMARD therapy in patients with early rheumatoid arthritis (RA). The study found that combination DMARD therapy for the first two years significantly limited peripheral joint damage for at least five years.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To evaluate the long-term frequency of disease remissions and the progression of joint damage in patients with early rheumatoid arthritis (RA) who were initially randomized to 2 years of treatment with either a combination of 3 disease-modifying antirheumatic drugs (DMARDs) or a single DM...See full text at original site
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引用元：
https://doi.org/10.1002/art.20351

データ提供：米国国立医学図書館（NLM）

Early Rheumatoid Arthritis: A Race Against Time

Rheumatoid arthritis, a chronic inflammatory disease, can have a devastating impact on joint health. Early diagnosis and aggressive treatment are crucial to prevent long-term joint damage. This research evaluates the long-term effectiveness of two different treatment strategies for early rheumatoid arthritis: a combination of three disease-modifying antirheumatic drugs (DMARDs) versus a single DMARD. The study provides valuable insights into the long-term frequency of disease remissions and the progression of joint damage in patients treated with these different approaches.

Aggressive Treatment: A Path Towards Remission in Early Rheumatoid Arthritis

This research demonstrates the long-term benefits of aggressive initial treatment with a combination of three DMARDs in patients with early rheumatoid arthritis. The study shows that this approach significantly limits peripheral joint damage for at least five years, potentially delaying the progression of the disease and improving long-term outcomes. The authors emphasize the importance of early intervention and aggressive treatment strategies in managing this chronic inflammatory disease.

Protecting Your Joints: A Guide to Managing Rheumatoid Arthritis

This research highlights the importance of early diagnosis and aggressive treatment in managing rheumatoid arthritis. The study demonstrates the long-term benefits of aggressive initial treatment with a combination of three DMARDs in preventing joint damage. This information can empower individuals with early rheumatoid arthritis to proactively engage in discussions with their healthcare providers and make informed decisions regarding their treatment plan.

Dr. Camel's Conclusion

This study demonstrates the long-term benefits of aggressive initial treatment with a combination of three DMARDs in patients with early rheumatoid arthritis, highlighting the importance of early intervention and aggressive treatment strategies in managing this chronic inflammatory disease.

Date :
  1. Date Completed 2004-08-13
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

15248204

DOI: Digital Object Identifier

10.1002/art.20351

Related Literature

Article Analysis
・Effective treatment of rheumatoid arthritis
SNS
PICO Info
in preparation
Languages

English

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