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Etanercept treatment of psoriatic arthritis: safety, efficacy, and effect on disease progression.

Author: BurchFrancis X, CohenStanley B, KivitzAlan J, MeasePhilip J, OryPeter, RubensteinJoel, SalonenDavid, SharpJohn T, SiegelEvan L, TsujiWayne

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Etanercept is a drug that is used to treat psoriatic arthritis (PsA). This study found that etanercept significantly reduced the signs and symptoms of PsA and psoriasis. It also inhibited radiographic disease progression and was well tolerated.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: Etanercept has been shown to improve the articular and cutaneous manifestations of psoriatic arthritis (PsA). In this study, we further evaluated the safety, efficacy, and effect on radiographic progression of etanercept in patients with PsA. METHODS: Patients with PsA (n = 205) were ran...See full text at original site
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引用元：
https://doi.org/10.1002/art.20335

データ提供：米国国立医学図書館（NLM）

Etanercept: A New Oasis in the Desert of Psoriatic Arthritis

Psoriatic arthritis (PsA), a chronic inflammatory disease that affects both the joints and the skin, can significantly impact a patient's quality of life. This research investigates the efficacy and safety of etanercept, a tumor necrosis factor (TNF) inhibitor, in managing PsA. The authors conducted a randomized controlled trial to evaluate etanercept's impact on the articular and cutaneous manifestations of PsA, as well as its effect on radiographic disease progression.

Etanercept: A Beacon of Hope for PsA Patients

The results of this study, like a refreshing oasis in the arid landscape of PsA, demonstrate the effectiveness of etanercept in reducing the signs and symptoms of PsA and psoriasis. The researchers found that etanercept significantly reduced joint symptoms, improved psoriatic lesions, and inhibited radiographic disease progression. These findings highlight the potential of etanercept to provide substantial relief for PsA patients.

Managing PsA: A Multi-faceted Approach

The authors' findings emphasize the importance of a multi-faceted approach to managing PsA. They recommend a combination of medication, lifestyle modifications, and ongoing monitoring to ensure optimal outcomes. The study reminds us that the journey to managing PsA is a long one, requiring ongoing collaboration between patients and healthcare providers to achieve lasting improvement.

Dr.Camel's Conclusion

This study, like a caravan traversing the vast desert of PsA research, provides valuable insights into the effectiveness of etanercept. The authors' findings highlight the potential of this drug to improve the quality of life for PsA patients, emphasizing the need for continued research and innovative therapies to manage this complex condition. Their work encourages us to embrace a multi-faceted approach to PsA care, ensuring the best possible outcomes for patients seeking relief from this debilitating disease.

Date :
  1. Date Completed 2004-08-13
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

15248226

DOI: Digital Object Identifier

10.1002/art.20335

Related Literature

Article Analysis
・Effective treatment of psoriatic arthritis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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