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Comparison of the pressor effect of tyramine after treatment with phenelzine and moclobemide in healthy male volunteers.

Author: GratzS S, SimpsonG M

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Moclobemide, a monoamine oxidase inhibitor, allowed subjects to tolerate high doses of tyramine without pressor effects, suggesting that it can be used without stringent dietary precautions.
Paper Details　
Original Abstract of the Article :
This study was conducted to establish the safety, tolerability, side effects, and pressor effects of tyramine on subjects treated with moclobemide, a short-acting reversible and preferential monoamine oxidase inhibitor, and to compare these responses with the responses of subjects treated with phene...See full text at original site
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引用元：
https://doi.org/10.1038/clpt.1992.143

データ提供：米国国立医学図書館（NLM）

Scopolamine for Preventing and Treating Motion Sickness

Motion sickness, a common ailment that plagues travelers and those prone to seasickness, is like a desert mirage that can leave you feeling nauseous and dizzy. This study examines the effectiveness of scopolamine, a medication used to prevent and treat motion sickness. Researchers conducted a systematic review, analyzing the available evidence to assess the efficacy of scopolamine in combating this unpleasant condition.

Scopolamine: A Potential Remedy for Motion Sickness?

The study found that scopolamine has been used for decades to treat and prevent motion sickness, but its effectiveness has not been systematically reviewed. While scopolamine has shown promise, the study suggests that further research is needed to fully understand its efficacy and identify the optimal doses for different individuals. It's like navigating a desert with a compass, seeking the best route to alleviate motion sickness while minimizing any potential side effects.

Navigating the Desert of Motion Sickness

The study highlights the need for a balanced approach to treating motion sickness. While scopolamine may offer relief, it's important to consider the potential side effects and explore other treatment options, such as behavioral therapies and complementary approaches. It's like finding a sustainable way to travel through the desert, ensuring a comfortable and safe journey.

Dr.Camel's Conclusion

This study provides a valuable overview of the use of scopolamine for motion sickness. While scopolamine has shown promise, the need for further research emphasizes the importance of a comprehensive approach to treating this condition. As we journey through the desert of motion sickness, we must explore various strategies to find the most effective and safest means of relief.

Date :
  1. Date Completed 1992-10-22
  2. Date Revised 2019-05-09
Further Info :

Pubmed ID

1526086

DOI: Digital Object Identifier

10.1038/clpt.1992.143

Related Literature

Article Analysis
・Side Effects of phenelzine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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