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Antagonizing the angiotensin II subtype 1 receptor: a focus on olmesartan medoxomil.
Author: KoikeHiroyuki, NussbergerJürg
Original Abstract of the Article :
BACKGROUND: The orally active, nonpeptide antagonists of the angiotensin II subtype 1 (AT1) receptor represent a recent class of antihypertensive drugs that selectively block the renin-angiotensin system. Olmesartan medoxomil is the newest member of this class. OBJECTIVE: This article reviews the r...See full text at original site
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引用元:
https://doi.org/10.1016/s0149-2918(04)90141-5
データ提供:米国国立医学図書館(NLM)
Antagonizing the Angiotensin II Subtype 1 Receptor: A Focus on Olmesartan Medoxomil
The renin-angiotensin system plays a crucial role in regulating blood pressure and other physiological processes. This research delves into the therapeutic potential of angiotensin II subtype 1 (AT1) receptor antagonists, a class of drugs that selectively block this system. The study focuses on olmesartan medoxomil, a newly developed AT1 receptor antagonist. Researchers reviewed key studies to illustrate the antihypertensive, cardioprotective, and renoprotective effects of olmesartan and compare its effects to other AT1 receptor antagonists and angiotensin-converting enzyme (ACE) inhibitors.
Olmesartan Medoxomil: A Promising Antihypertensive Agent
This study provides a comprehensive overview of the therapeutic potential of olmesartan medoxomil. Researchers demonstrate its potent and selective action as an AT1 receptor antagonist, leading to a significant reduction in blood pressure. Furthermore, olmesartan medoxomil exhibits cardioprotective and renoprotective effects, making it a valuable therapeutic option for individuals with hypertension and other cardiovascular and renal diseases.
Protecting the Heart and Kidneys: The Benefits of Olmesartan Medoxomil
This study highlights the multifaceted benefits of olmesartan medoxomil. By selectively blocking the AT1 receptor, this drug effectively lowers blood pressure and offers protection against cardiovascular and renal complications. It's like building a sturdy wall to protect the heart and kidneys from the damaging effects of hypertension.
Dr. Camel's Conclusion
This research presents a compelling case for the use of olmesartan medoxomil in the management of hypertension and related conditions. The study demonstrates the drug's potent antihypertensive, cardioprotective, and renoprotective effects. As researchers, we are constantly striving to improve cardiovascular health. This study offers valuable insights into the potential of olmesartan medoxomil to contribute to this ongoing mission. It's like finding a rare desert plant with medicinal properties that can heal and protect the body.
Date :
- Date Completed 2004-08-30
- Date Revised 2019-09-22
Further Info :
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