Paper Details

  1. Home
  2. Paper Details

Migraine: pathophysiology, pharmacology, treatment and future trends.

Author: CenturiónDavid, SaxenaPramod R, ValdiviaLuis Felipe, VillalónCarlos M, de VriesPeter

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Historical ArticleA research paper that analyzes past events and developments using primary sources and examines them from a historical perspective.

Overview

This review discusses the treatment of migraine, highlighting the role of serotonin and the development of triptans, a new class of drugs that are selective 5-HT1B/1D/1F receptor agonists. It also explores the potential of other antimigraine alternatives, such as CGRP receptor antagonists and 5-HT7 receptor antagonists.
Paper Details　
Original Abstract of the Article :
Migraine treatment has evolved into the scientific arena, but it seems still controversial whether migraine is primarily a vascular or a neurological dysfunction. Irrespective of this controversy, the levels of serotonin (5-hydroxytryptamine; 5-HT), a vasoconstrictor and a central neurotransmitter, ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.2174/1570161033386826

データ提供：米国国立医学図書館（NLM）

Navigating the Migraine Desert: A Journey Through Pathophysiology and Treatment

Migraine, a debilitating headache disorder, is like a desert sandstorm, leaving its victims feeling disoriented and lost. This review article delves into the complex world of migraine, exploring its pathophysiology, pharmacology, and treatment. The author, like a skilled desert guide, leads us through a comprehensive journey, covering the intricate mechanisms of migraine and highlighting the evolution of treatment approaches.

A Desert Oasis of Knowledge: Understanding Migraine

This review, like a well-stocked desert caravan, provides a wealth of knowledge about migraine. The author meticulously explores the underlying mechanisms of this debilitating condition, covering both the vascular and neurological theories. This comprehensive approach, like a detailed map of a vast desert, helps us understand the complexities of migraine and the challenges of finding effective treatments.

Finding Relief in the Migraine Desert: Treatment Strategies

Migraine, like a relentless desert sandstorm, can significantly impact a person's quality of life. This review provides valuable insights into the evolution of migraine treatments, highlighting the development of triptans, a class of medications specifically designed to target migraine pain. By understanding the various treatment options available, individuals can navigate this challenging landscape and find relief from the debilitating effects of migraine.

Dr. Camel's Conclusion

This review, like a desert oasis, offers a comprehensive understanding of migraine, a complex and often debilitating headache disorder. The author, like a skilled desert guide, expertly navigates the intricate mechanisms of migraine, highlighting the evolution of treatment approaches. This detailed journey through the world of migraine provides valuable insights for both patients and healthcare professionals, offering a roadmap for understanding and managing this challenging condition.

Date :
  1. Date Completed 2004-12-01
  2. Date Revised 2022-04-10
Further Info :

Pubmed ID

15320857

DOI: Digital Object Identifier

10.2174/1570161033386826

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.