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Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial): randomised controlled trial.

Author: , BourassaMartial G, ClaytonTim C, DanchinNicolas, DartAnthony M, FoxKeith A A, HildebrandtPer, HjalmarsonAke, JustHanjörg, KirwanBridget-Anne, KragtenJohannes A, LubsenJacobus, MolhoekG Peter, MotroMichael, OtterstadJan-Erik, ParkerJohn D, PocockStuart J, Poole-WilsonPhilip A, Seabra-GomesRicardo, Soler-SolerJordi, WagenerGilbert, WeberSimon, van DalenFred J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Addition of nifedipine GITS to conventional treatment of angina pectoris has no effect on major cardiovascular event-free survival. Nifedipine GITS is safe and reduces the need for coronary angiography and interventions.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Calcium antagonists are widely prescribed for angina pectoris but their effect on clinical outcome is controversial. We aimed to investigate the effect of the calcium antagonist nifedipine on long-term outcome in patients with stable angina pectoris. METHODS: We randomly assigned 3825 p...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/15351192

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 2004-09-21
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

15351192

DOI: Digital Object Identifier

S0140-6736(04)16980-8

Related Literature

Article Analysis
・Effective treatment of angina
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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