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Cognitive response to pharmacological treatment for depression in Alzheimer disease: secondary outcomes from the depression in Alzheimer's disease study (DIADS).
Author: BrandtJason, LyketsosConstantine G, MunroCynthia A, RabinsPeter V, SamusQuincy M, SheppardJeannie-Marie E, SteeleCynthia D, SteinbergMartin
Original Abstract of the Article :
OBJECTIVE: The authors assessed the cognitive effects of depression treatment with sertraline in patients with Alzheimer disease (AD) and major depression. METHODS: Forty-four patients with probable AD and major depression were enrolled in a double-blind, placebo-controlled clinical trial of sertra...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元:
https://pubmed.ncbi.nlm.nih.gov/15353387
データ提供:米国国立医学図書館(NLM)
Treating Depression in Alzheimer's Disease: A Complex Landscape
The field of [Alzheimer's disease] is grappling with the challenge of treating [depression] in this vulnerable population. This study explores the [cognitive effects] of [sertraline] treatment for [depression] in patients with [Alzheimer's disease]. The researchers conducted a [double-blind, placebo-controlled clinical trial] to assess the impact of [sertraline] on [cognition] and [mood]. Their findings reveal a complex relationship between [depression treatment], [cognition], and [Alzheimer's disease], highlighting the need for further research into personalized approaches.
Depression Treatment and Cognition in Alzheimer's Disease: A Complex Interplay
The study's results reveal a nuanced picture of the impact of [depression treatment] on [cognition] in patients with [Alzheimer's disease]. While there was no overall association between [improved mood] and [cognitive improvement], a [sex difference] emerged, with [women] treated with [sertraline] showing [cognitive improvement] compared to placebo, while [men] treated with [sertraline] showed [cognitive decline] compared to placebo. This highlights the potential for sex-specific responses to [depression treatment] in [Alzheimer's disease] and the need for further investigation.
Navigating the Shifting Sands of Alzheimer's: Personalized Approaches to Treatment
This research, like a map navigating a shifting desert landscape, underscores the complexity of treating [depression] in patients with [Alzheimer's disease]. The findings highlight the potential for [sex-specific responses] to [depression treatment] and underscore the need for personalized approaches. It's crucial to understand the unique needs and characteristics of each patient to optimize treatment outcomes and support their overall well-being.
Dr.Camel's Conclusion
Alzheimer's disease, like a vast and unforgiving desert, presents a formidable challenge for patients and clinicians alike. This study reveals the complex interplay between depression treatment, cognition, and Alzheimer's disease, highlighting the need for personalized approaches. Understanding the nuances of this relationship is crucial for navigating the shifting sands of this disease and providing the best possible care for those affected.
Date :
- Date Completed 2005-01-24
- Date Revised 2022-12-07
Further Info :
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