Paper Details 
Original Abstract of the Article :
Components of the renin-angiotensin system, and the ability to synthesize these components locally, have been demonstrated in cardiovascular tissues. Locally generated angiotensin II may affect vascular tone, regional blood flow, cardiac contractility, and vascular and cardiac growth. Local renin-an...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1016/0002-9149(92)90275-4

データ提供:米国国立医学図書館(NLM)

Angiotensin-Converting Enzyme: A Key Player in Blood Pressure Regulation

This study explores the role of angiotensin-converting enzyme (ACE) in regulating blood pressure, focusing on its presence and function in cardiovascular and adrenal tissues. The research highlights the importance of local ACE activity in influencing vascular tone, blood flow, cardiac contractility, and tissue growth. It also discusses the implications of ACE inhibitors, a class of medications used to treat high blood pressure, on both local and systemic ACE activity.

ACE Inhibitors: Tailoring Blood Pressure Treatment

The study emphasizes the potential for individualizing blood pressure treatment by considering tissue-specific effects of ACE inhibitors. The researchers suggest that targeting ACE activity in specific tissues, like the vasculature, could be a more effective strategy for managing blood pressure. The results underscore the need for further research to optimize the use of ACE inhibitors and improve patient outcomes.

Understanding ACE: A Key to Blood Pressure Management

This research provides valuable insights into the complex role of ACE in blood pressure regulation. Understanding the tissue-specific effects of ACE inhibitors could lead to more personalized treatment approaches, potentially improving efficacy and reducing side effects. The findings emphasize the importance of considering the entire picture when treating high blood pressure, acknowledging the role of local ACE activity and the potential impact of ACE inhibitors on different tissues.

Dr.Camel's Conclusion

Imagine the body's circulatory system as a vast desert, with ACE playing a vital role in regulating the flow of blood like a carefully orchestrated irrigation system. This research sheds light on the local effects of ACE in various tissues, suggesting that targeted therapies could be more effective than general approaches. It's like finding a hidden oasis in the desert, allowing us to fine-tune treatment strategies for optimal blood pressure control.

Date :
  1. Date Completed 1992-04-15
  2. Date Revised 2019-06-22
Further Info :

Pubmed ID

1546636

DOI: Digital Object Identifier

10.1016/0002-9149(92)90275-4

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.