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[Results of a double-blind medium-term study comparing effects of timolol maleate and epinephrine in 120 patients with chronic open-angle glaucoma].

Author: DemaillyP, EtienneR, HautJ, LehnerM A, MassinM, RaynaudG, TatryC, TrepsatC

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Timolol was more effective than epinephrine in controlling chronic open-angle glaucoma. Good tonometric control was achieved in 81.6% of patients treated with timolol compared to 52.5% of those receiving epinephrine. No side effects were observed.
Paper Details　
Original Abstract of the Article :
A double-blind medium term study of the activity of timolol in chronic open-angle glaucoma was conducted in four French ophthalmological centers, using the same protocol. A total of 119 patients were treated: --60 with timolol; --59 with épinéphrine, for comparison. Results showed a significantly su...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/155097

データ提供：米国国立医学図書館（NLM）

Comparing Timolol Maleate and Epinephrine for Chronic Open-Angle Glaucoma

This study delves into the fascinating realm of ophthalmology, exploring the effectiveness of two different medications, timolol maleate and epinephrine, in treating chronic open-angle glaucoma, a condition that can lead to vision loss. The researchers conducted a double-blind, medium-term study involving 119 patients, comparing the efficacy of these medications. Their findings revealed a significant superiority of timolol over epinephrine in achieving good tonometric control, a crucial measure of intraocular pressure management. The study also highlighted the safety profile of timolol, reporting no significant side effects.

Timolol: A Shining Beacon in Glaucoma Treatment

The study's results demonstrate the effectiveness of timolol in managing chronic open-angle glaucoma. The significantly higher success rate of timolol in achieving good tonometric control compared to epinephrine, coupled with its safety profile, positions timolol as a promising therapeutic option. This research provides valuable insights for ophthalmologists seeking effective treatments for glaucoma patients.

Vision Care and Glaucoma Management: A Comprehensive Approach

The study reminds us that the desert of glaucoma can be vast and challenging, but with the right tools, we can find paths towards vision preservation. It is crucial for individuals with glaucoma to consult with ophthalmologists and explore treatment options like timolol, while adhering to regular eye exams and lifestyle recommendations for managing the disease. By adopting a comprehensive approach, we can strive to preserve our precious gift of sight.

Dr.Camel's Conclusion

Like the desert traveler who relies on a sturdy camel for a safe journey, glaucoma patients can find solace in the effectiveness of timolol, a medication that has proven its worth in managing this vision-threatening condition. While the desert may be vast and unforgiving, this research provides us with a beacon of hope, guiding us towards better vision care and a brighter future.

Date :
  1. Date Completed 1979-06-26
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

155097

DOI: Digital Object Identifier

155097

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Article Analysis
・Effects of timolol
SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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