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Antiretrovirals, Part II: focus on non-protease inhibitor antiretrovirals (NRTIs, NNRTIs, and fusion inhibitors).

Author: ArmstrongScott C, CozzaKelly L, WortmannGlenn W, WynnGary H, ZaporMichael J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review summarizes non-protease inhibitor antiretroviral drugs, including nucleoside and nucleotide analogue reverse transcriptase inhibitors (NRTIs), nonnucleoside reverse transcriptase inhibitors (NNRTIs), and cell membrane fusion inhibitors. It explains how these drugs work, their side effects, toxicities, and drug interactions.
Paper Details　
Original Abstract of the Article :
The second in a series reviewing the HIV/AIDS antiretroviral drugs. This review summarizes the non-protease inhibitor antiretrovirals: nucleoside and nucleotide analogue reverse transcriptase inhibitors (NRTIs), the nonnucleoside reverse transcriptase inhibitors (NNRTIs), and cell membrane fusion in...See full text at original site
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引用元：
https://doi.org/10.1176/appi.psy.45.6.524

データ提供：米国国立医学図書館（NLM）

Antiretrovirals: A Vital Tool for HIV/AIDS Management

The development of [antiretroviral drugs] has revolutionized the treatment and management of [HIV/AIDS]. This article provides a comprehensive overview of [non-protease inhibitor antiretrovirals], including [nucleoside and nucleotide analogue reverse transcriptase inhibitors (NRTIs), nonnucleoside reverse transcriptase inhibitors (NNRTIs), and cell membrane fusion inhibitors]. It discusses the mechanisms of action, side effects, toxicities, and drug interactions of these agents, providing valuable information for healthcare professionals.

Understanding Non-Protease Inhibitor Antiretrovirals

The article explains how these drugs work to inhibit different stages of the HIV life cycle, ultimately preventing the virus from replicating and spreading. It also discusses the potential side effects and toxicities associated with each class of antiretrovirals, emphasizing the importance of careful monitoring and patient education. This knowledge empowers healthcare providers to make informed decisions regarding the choice and management of antiretroviral therapy.

A Collaborative Approach to HIV/AIDS Management

This article highlights the importance of a collaborative approach to HIV/AIDS management, involving healthcare providers, patients, and researchers. Imagine a camel caravan navigating a challenging desert landscape. Success requires a shared understanding of the terrain, a clear plan, and effective communication between all members of the caravan. Similarly, managing HIV/AIDS effectively requires a collaborative effort to ensure the best possible outcomes for patients.

Dr.Camel's Conclusion

This article is a testament to the remarkable progress made in the treatment of HIV/AIDS. It underscores the importance of ongoing research and development of new antiretroviral therapies to combat the virus and improve the lives of those affected by the disease. By working together, we can continue to navigate the desert of HIV/AIDS and create a brighter future for all.

Date :
  1. Date Completed 2005-01-04
  2. Date Revised 2020-12-09
Further Info :

Pubmed ID

15546830

DOI: Digital Object Identifier

10.1176/appi.psy.45.6.524

SNS
PICO Info
in preparation
Languages

English

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