Analgesic effects of low-dose intravenous orphenadrine in the state of capsaicin hyperalgesia. A randomised, placebo-controlled, double-blind cross-over study using laser somatosensory evoked potentials obtained from capsaicin-irritated skin in healthy volunteers.

Author: ReitmeirPeter, SchafflerKlaus

Paper Details 
Original Abstract of the Article :
The present investigation aimed to elucidate the analgesic efficacy of 30 mg of intravenous orphenadrine citrate (CAS 4682-36-4) in a human pain model. Eighteen healthy female and male subjects were enrolled and received single infusions of 30 mg orphenadrine citrate and matching placebo in two peri...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1055/s-0031-1297020

データ提供:米国国立医学図書館(NLM)

Orphenadrine for Pain Relief: A New Oasis in the Desert of Pain Management

The desert of pain management is vast and often challenging, with patients seeking relief from various forms of discomfort. This study investigates the potential of orphenadrine, a medication traditionally used for muscle spasms, as a new weapon against pain.

Orphenadrine Shows Promise in Reducing Pain

The researchers found that orphenadrine, even at low doses, effectively reduced pain in a model of capsaicin-induced hyperalgesia. This discovery suggests that orphenadrine may have broader applications in pain management than previously thought, potentially offering a new oasis in the desert of pain relief.

Exploring New Avenues for Pain Relief

This study provides valuable insights into the potential therapeutic applications of orphenadrine. It encourages further research to explore the full range of its analgesic effects and to develop new strategies for pain management.

Dr.Camel's Conclusion

This research is like discovering a hidden spring in the vast desert of pain management. Orphenadrine, a seemingly ordinary camel, may hold the key to reducing pain, offering a new path to relief for those suffering from discomfort. This study reminds us that the desert of medical knowledge is full of surprises, and that we must continue to explore new possibilities for treating pain.

Date :
  1. Date Completed 2005-01-11
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

15553107

DOI: Digital Object Identifier

10.1055/s-0031-1297020

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.