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Chemoradiotherapy for primary CNS lymphoma: an intent-to-treat analysis with complete follow-up.
Author: AbreyLauren E, DeAngelisLisa M, OmuroAntonio M P, YahalomJoachim
Original Abstract of the Article :
OBJECTIVE: To assess the efficacy and safety of a preradiation chemotherapy regimen in patients with primary CNS lymphoma (PCNSL), with emphasis on long-term outcomes. METHODS: In this prospective phase II trial, patients with a new diagnosis of PCNSL received two cycles of intrathecal (12 mg) and ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1212/01.WNL.0000148641.98241.5E
データ提供:米国国立医学図書館(NLM)
Combating Primary CNS Lymphoma: A Multimodal Approach
Dr. Camel here, ready to explore the world of primary central nervous system lymphoma (PCNSL), a challenging type of cancer that affects the brain and spinal cord. This research examines the efficacy and safety of a multimodal treatment regimen combining chemotherapy and radiation therapy for PCNSL. It's like a desert expedition, employing a multi-pronged approach to battle a formidable foe.
A Combined Strategy
The study explores the effectiveness of a preradiation chemotherapy regimen followed by whole-brain radiotherapy. It's a combined effort, like a caravan of camels working together to overcome obstacles in a harsh desert. The research reveals promising results, showing a high rate of complete response after treatment, demonstrating the potential of this multimodal approach to effectively combat PCNSL.
Challenges and Long-Term Outcomes
While the study highlights the effectiveness of this treatment regimen, it also acknowledges the challenges associated with long-term outcomes. The research emphasizes the importance of continued monitoring and follow-up to address potential relapses. It's a continuous journey through the desert of cancer treatment, requiring vigilance and ongoing care. The study also underscores the need for research into strategies to minimize neurotoxicity, a common side effect of treatment. It's a quest for more effective and safer treatments, like seeking a hidden oasis of hope in a vast desert.
Dr. Camel's Conclusion
This research offers a valuable contribution to the field of PCNSL treatment, highlighting the potential of a multimodal approach combining chemotherapy and radiation therapy. It's a testament to the ongoing quest for better treatments for this challenging disease, reminding us that the journey through the desert of cancer research is a continuous one, requiring persistent exploration and innovation to find more effective and safer solutions.
Date :
- Date Completed 2005-09-27
- Date Revised 2013-11-21
Further Info :
Related Literature
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