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Long-term antidepressant treatment with moclobemide for aphasia in acute stroke patients: a randomised, double-blind, placebo-controlled study.

Author: HellblomA, KahanT, LaskaA C, MurrayV, von ArbinM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The study investigated whether antidepressive drug therapy could enhance regression from aphasia after acute stroke.
Paper Details　
Original Abstract of the Article :
Pharmacotherapy aimed at stroke rehabilitation through direct central nervous effects may be assumed to work in a similar way for language recovery and sensory-motor recovery. Some data suggest that antidepressant drugs could be beneficial also for functional improvement. This prompted us to investi...See full text at original site
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引用元：
https://doi.org/10.1159/000083256

データ提供：米国国立医学図書館（NLM）

Exploring the Potential of Moclobemide for Aphasia Recovery after Stroke

Stroke is a devastating event that can lead to various complications, including aphasia, a language disorder that can significantly impact communication and social interaction. This study explores the potential of long-term antidepressant treatment with moclobemide to enhance aphasia recovery in acute stroke patients.

Researchers, like explorers navigating the complex landscape of stroke recovery, sought to understand if antidepressant therapy could play a role in language rehabilitation. They hypothesized that moclobemide, an antidepressant, could potentially promote functional improvement, including language recovery.

A New Path for Aphasia Rehabilitation

The study's findings suggest that moclobemide may not significantly enhance aphasia recovery after acute stroke. While the study found no significant difference between the moclobemide and placebo groups, it highlights the need for further research to explore the potential role of antidepressant therapy in aphasia rehabilitation. This is a journey that requires continued exploration and innovative approaches to find the most effective solutions for stroke recovery.

Understanding the Complexities of Stroke Recovery

This research underscores the complexities of stroke recovery, particularly in relation to aphasia. It emphasizes the need for multidisciplinary approaches to rehabilitation, incorporating various therapies and strategies to address the individual needs of stroke survivors.

Dr.Camel's Conclusion

This study explores the potential of moclobemide for aphasia recovery after stroke. While the study found no significant difference between the moclobemide and placebo groups, it highlights the need for further research to understand the potential role of antidepressant therapy in this complex area of rehabilitation. It's a reminder that the journey to recovery after stroke can be challenging, requiring ongoing research and a multidisciplinary approach to provide the best possible care for stroke survivors.

Date :
  1. Date Completed 2005-04-28
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

15644624

DOI: Digital Object Identifier

10.1159/000083256

Related Literature

Article Analysis
・Effective treatment of stroke rehabilitation
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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