Effect of plant sterols and endurance training on LDL particle size and distribution in previously sedentary hypercholesterolemic adults.

Author: JonesP J H, LamarcheB, St-PierreA C, VaradyK A

Paper Details 
Original Abstract of the Article :
BACKGROUND: Plant sterols and exercise favourably alter lipid profiles in a way that protect against future coronary heart disease (CHD). However, their effects on other indicators of CHD risk, such as LDL particle size, still need further clarification. OBJECTIVE: This study examined the effect of...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1038/sj.ejcn.1602106

データ提供:米国国立医学図書館(NLM)

Plant Sterols and Exercise for Hypercholesterolemia: Impact on LDL Particle Size

This study investigated the combined effects of plant sterols and endurance training on LDL particle size and distribution in previously sedentary adults with hypercholesterolemia. Participants were randomly assigned to four groups: plant sterols and exercise, exercise only, plant sterols only, or a control group.

The study found that exercise significantly reduced LDL peak particle size and decreased the proportion of large LDL particles. Plant sterols, on the other hand, did not significantly alter LDL particle size distribution but did reduce cholesterol concentrations within all LDL particle sizes.

LDL Particle Size: A Key Indicator of Heart Disease Risk

LDL particle size is an important indicator of heart disease risk. Smaller LDL particles are more likely to penetrate the arterial walls, contributing to plaque formation and increasing the risk of heart disease.

Managing Cholesterol: A Combined Approach

This study highlights the potential benefits of a combined approach to managing cholesterol levels. While both plant sterols and exercise can have positive effects, they seem to work in different ways. A combination of these interventions may offer the most effective strategy for reducing heart disease risk.

Dr. Camel's Conclusion

This study reminds us that a healthy lifestyle, like a camel's endurance in the desert, is essential for maintaining good health. The findings suggest that combining plant sterols and exercise may offer a powerful strategy for managing cholesterol levels and reducing heart disease risk. As a researcher, I am always impressed by the intricate ways in which our bodies respond to diet and exercise.

Date :
  1. Date Completed 2005-09-20
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

15674305

DOI: Digital Object Identifier

10.1038/sj.ejcn.1602106

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.