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MORE--MOexipril and REgression of left ventricle hypertrophy in combination therapy A multicentric open label clinical trial.

Author: , SpinarJ, VítovecJ

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Overview

The ACE inhibitor moexipril added to combination therapy for hypertension had a similar effect on blood pressure reduction and left ventricle mass as in monotherapy trials. The most effective combination was ACE inhibitor plus thiazide diuretic.
Paper Details　
Original Abstract of the Article :
AIM: To evaluate the effect of ACE inhibitor moexipril if added to combination therapy in patient with poorly controlled hypertension. PATIENTS: Four hundred twenty patients with hypertension treated with monotherapy or two dug combination without an ACE inhibitor or AII antagonist and with blood p...See full text at original site
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引用元：
https://doi.org/10.1016/j.ijcard.2004.05.077

データ提供：米国国立医学図書館（NLM）

Moexipril: A Potent Tool for Managing Hypertension and Left Ventricle Hypertrophy

Hypertension, or high blood pressure, is a widespread health concern that can lead to heart problems and other complications. This study explores the effectiveness of [moexipril], an [ACE inhibitor], in combination therapy for poorly controlled hypertension. The researchers studied the effects of adding moexipril to existing treatments on blood pressure, heart rate, and left ventricle hypertrophy, a condition where the heart muscle thickens. The study demonstrates that moexipril, when added to combination therapy, significantly reduces blood pressure and left ventricle mass.

Combating Hypertension: Exploring the Benefits of Moexipril

The results show that moexipril, when added to existing treatment regimens for hypertension, effectively lowers blood pressure and reduces left ventricle mass. This positive impact is observed across a range of combination therapies, with the most noticeable benefit seen when moexipril is combined with [thiazide diuretics].

Maintaining Heart Health: A Journey of Awareness and Action

As a camel who traverses vast distances, I understand the importance of a healthy heart. This research underscores the potential of moexipril in managing hypertension and reducing the risk of heart problems. It highlights the significance of [regular blood pressure monitoring] and [working closely with healthcare providers] to ensure optimal treatment.

Dr.Camel's Conclusion

This study provides compelling evidence that moexipril, when added to combination therapy, effectively manages hypertension and reduces left ventricle hypertrophy. These findings highlight the importance of individualized treatment plans for hypertension, considering factors like existing medications and patient response.

Date :
  1. Date Completed 2005-07-25
  2. Date Revised 2014-01-09
Further Info :

Pubmed ID

15823625

DOI: Digital Object Identifier

10.1016/j.ijcard.2004.05.077

Related Literature

Article Analysis
・Effects of moexipril
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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