Intraarticular corticosteroid for treatment of osteoarthritis of the knee.

Author: BellamyN, BourneR, CampbellJ, GeeT, RobinsonV, WellsG

Paper Details 
Original Abstract of the Article :
BACKGROUND: Osteoarthritis (OA) is a common joint disorder. In the knee, injections of corticosteroids into the joint (intra-articular (IA)) may relieve inflammation, and reduce pain and disability. OBJECTIVES: To evaluate the efficacy and safety of IA corticosteroids in treatment of OA of the knee...See full text at original site
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引用元:
https://doi.org/10.1002/14651858.CD005328

データ提供:米国国立医学図書館(NLM)

Intra-Articular Corticosteroids: A Treatment Option for Osteoarthritis of the Knee

Osteoarthritis (OA) is a degenerative joint disease that affects millions of people worldwide, often causing pain, stiffness, and limitations in mobility. This research examines the efficacy and safety of intra-articular (IA) corticosteroids, which are injected directly into the joint, as a treatment for OA of the knee.

The study reviewed 26 randomized controlled trials involving over 1,700 participants. The results showed that IA corticosteroids were more effective than placebo in reducing pain and improving patient global assessment in the short term (up to one week after injection). However, the long-term benefits of IA corticosteroids were less clear, with evidence suggesting that the effects may not be as durable as those observed with other treatments, such as hyaluronic acid (HA) products.

Short-Term Benefits, Long-Term Uncertainties

The study highlights the short-term effectiveness of IA corticosteroids in alleviating pain and improving patient-reported outcomes in OA of the knee. However, it also raises concerns regarding the long-term durability of these effects, suggesting that other treatment options, such as HA products, may be more suitable for long-term management. The study emphasizes the need for further research to better understand the long-term effects of IA corticosteroids.

Understanding Treatment Options for OA

This research provides valuable insight into the use of IA corticosteroids for OA of the knee. It emphasizes the need for careful consideration of both short-term and long-term treatment goals when deciding on the most appropriate course of action. The study encourages individuals to discuss their options with their healthcare providers to make informed decisions based on their specific needs and preferences.

Dr.Camel's Conclusion

Just as a camel can navigate the desert with a careful balance of short-term and long-term strategies, the treatment of OA requires a thoughtful approach. This research provides valuable information to help patients and clinicians make informed choices about managing this common and often debilitating condition.

Date :
  1. Date Completed 2005-07-19
  2. Date Revised 2018-12-21
Further Info :

Pubmed ID

15846755

DOI: Digital Object Identifier

10.1002/14651858.CD005328

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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