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Comparison of blood pressure control with amlodipine and controlled-release isradipine: an open-label, drug substitution study.

Author: GanzMichael, MokabberiRasoul, SicaDomenic A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Controlled-release isradipine was more effective in controlling blood pressure and reduced edema rates in patients with mild-to-moderate hypertension compared to amlodipine.
Paper Details　
Original Abstract of the Article :
An open-label drug substitution study showed that controlled-release isradipine (Dynacirc-CR) can be safely substituted for amlodipine on a mg-for-mg basis in patients with mild-to-moderate hypertension. When controlled-release isradipine was substituted for amlodipine, blood pressure was more effec...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109349/

データ提供：米国国立医学図書館（NLM）

Comparing Amlodipine and Controlled-Release Isradipine for Hypertension

This open-label drug substitution study compares the efficacy and safety of controlled-release isradipine (Dynacirc-CR) and amlodipine, both medications used to treat hypertension, or high blood pressure. The study explores the effectiveness of switching patients from amlodipine to controlled-release isradipine on a mg-for-mg basis.

Controlled-Release Isradipine Offers Improved Blood Pressure Control

The study found that controlled-release isradipine effectively controlled blood pressure and resulted in fewer cases of edema (swelling) compared to amlodipine. These findings suggest that controlled-release isradipine may be a more favorable treatment option for some hypertensive patients.

Navigating the Desert of Blood Pressure

Imagine hypertension as a vast and treacherous desert, where high blood pressure can lead to a variety of health problems. This study offers a new guide, exploring the effectiveness of controlled-release isradipine as a potential path to managing blood pressure. It highlights the importance of considering different medications and their individual characteristics to find the best treatment for each patient.

Dr. Camel's Conclusion

This study provides valuable information for physicians and patients considering treatment options for hypertension. It highlights the potential benefits of controlled-release isradipine and underscores the importance of personalized treatment approaches for managing this common condition.
Date :
  1. Date Completed 2005-08-04
  2. Date Revised 2021-12-17
Further Info :

Pubmed ID

15858400

DOI: Digital Object Identifier

PMC8109349

Related Literature

Article Analysis
・Side Effects of isradipine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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