A randomized clinical trial of valacyclovir in multiple sclerosis.

Author: AblashiD, EdgellR, FriedmanJ E, PlankC, RapalinoO, ShahanB, ShengD, ShiehM, WhitmanJ, ZabriskieJ B, ZimmermanR

Paper Details 
Original Abstract of the Article :
The human Herpesvirus type-6 (HHV-6) has been implicated in multiple sclerosis (MS). Valacyclovir is an antiviral agent with an excellent safety profile. A two-year placebo-controlled, double-blind study was conducted to (1) ascertain if high-dose, prolonged treatment with valacyclovir would be safe...See full text at original site
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引用元:
https://doi.org/10.1191/1352458505ms1185oa

データ提供:米国国立医学図書館(NLM)

Valacyclovir and Multiple Sclerosis: Seeking Relief in a Complex Desert

The world of multiple sclerosis (MS) is a challenging desert, with many researchers searching for effective treatments to alleviate the symptoms of this debilitating disease. This study investigates the potential of valacyclovir, an antiviral agent, to impact the course of MS. The research employs a rigorous double-blind, placebo-controlled study, a well-established methodology for ensuring objectivity in evaluating the effectiveness of interventions. It's like navigating a complex desert landscape with a careful map to guide the way.

While the study found that valacyclovir was safe for prolonged use, it did not demonstrate a significant delay in the progression of MS, either clinically or through magnetic resonance imaging (MRI). The results are like finding a dry riverbed in the desert, suggesting that valacyclovir, while safe, may not be the key to unlocking the secrets of MS treatment.

Valacyclovir and Multiple Sclerosis: A Journey Through the Desert of Uncertainty

The study highlights the complexity of MS and the ongoing search for effective treatments. It's like navigating a vast desert, where the path to a cure is still shrouded in uncertainty. The research underscores the need for continued exploration and innovative approaches in the fight against this debilitating disease.

Navigating the Desert of Multiple Sclerosis: Seeking New Pathways to Treatment

This study underscores the need for continued research to develop effective treatments for MS. It's like finding a new path through a challenging desert landscape, offering hope for a brighter future. The study also highlights the importance of safety in medical interventions, ensuring that treatments are not only effective but also safe for patients.

Dr. Camel's Conclusion

This study provides valuable insights into the safety and potential efficacy of valacyclovir in managing MS. It's like a compass guiding researchers through the desert of uncertainty, highlighting the need for continued exploration and innovative approaches in the fight against this complex disease.

Date :
  1. Date Completed 2005-07-15
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

15957509

DOI: Digital Object Identifier

10.1191/1352458505ms1185oa

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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