Risperidone and haloperidol augmentation of serotonin reuptake inhibitors in refractory obsessive-compulsive disorder: a crossover study.

Author: BaxterLewis R, FlournoyJames M, JacksonWarren T, LiXiaohua, MayRoberta S, TolbertLelland C

Paper Details 
Original Abstract of the Article :
Although serotonin reuptake inhibitors (SRIs) are the first-line treatment for obsessive-compulsive disorder (OCD), approximately half of patients with OCD do not respond adequately to SRI monotherapy. Patients with predominant obsessions are common in OCD and are often difficult to treat, necessita...See full text at original site
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引用元:
https://doi.org/10.4088/jcp.v66n0610

データ提供:米国国立医学図書館(NLM)

Augmenting Serotonin Reuptake Inhibitors (SRIs) for Refractory Obsessive-Compulsive Disorder (OCD): A Quest for Serenity in the Desert of OCD

This crossover study explores the effectiveness of augmenting serotonin reuptake inhibitors (SRIs), the first-line treatment for obsessive-compulsive disorder (OCD), with risperidone or haloperidol in patients with refractory OCD, those who do not respond adequately to SRI monotherapy. The study focused on patients with predominant obsessions, often a difficult-to-treat subgroup of OCD patients. The researchers observed that augmenting SRIs with risperidone or haloperidol resulted in significant symptom reduction in patients with refractory OCD, suggesting that these augmentation strategies may be effective in treating this challenging condition. The study's findings are like a hidden oasis in the vast desert of OCD, offering a potential solution to a condition that can significantly impact quality of life.

Augmentation Strategies: A Possible Route to Relief in the Desert of OCD

The study's findings provide valuable insights into the potential benefits of augmenting SRIs with risperidone or haloperidol in treating refractory OCD. This research underscores the importance of exploring alternative treatment strategies for those who do not respond adequately to conventional therapies. It's like discovering a new path through the desert of OCD, offering hope for those seeking relief from their symptoms.

Personalized Treatment for OCD

This research highlights the need for personalized treatment approaches for OCD, considering the individual needs and responses of each patient. The study's findings encourage further research into the efficacy of different augmentation strategies for refractory OCD, paving the way for more effective treatments for those struggling with this debilitating condition. This research is a testament to the ongoing quest for better treatments for OCD, a reminder that in the vast desert of this condition, there may be many hidden oases of relief waiting to be discovered.

Dr.Camel's Conclusion

The study's findings suggest that augmenting SRIs with risperidone or haloperidol may be an effective treatment strategy for refractory OCD. This research is like a beacon of hope in the desert of OCD, illuminating a path towards more effective treatment options for those struggling with this challenging condition.

Date :
  1. Date Completed 2005-08-04
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

15960567

DOI: Digital Object Identifier

10.4088/jcp.v66n0610

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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