Comparison of the analgesic effects of a fixed-dose combination of orphenadrine and diclofenac (Neodolpasse) with its single active ingredients diclofenac and orphenadrine: a placebo-controlled study using laser-induced somatosensory-evoked potentials from capsaicin-induced hyperalgesic human skin.

Author: EggenreichUdo, GschanesAndrea, ReitmeirPeter, SchafflerKlaus

Paper Details 
Original Abstract of the Article :
OBJECTIVE: The aim of this study was to investigate the analgesic efficacy of Neodolpasse, a fixed-dose combination of orphenadrine and diclofenac, compared with those of its single active ingredients in a human pain model. METHODS: The study was designed as a randomised, double-blind, placebo-cont...See full text at original site
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引用元:
https://doi.org/10.2165/00126839-200506040-00001

データ提供:米国国立医学図書館(NLM)

Pain Relief: A Winning Combination of Orphenadrine and Diclofenac

Pain can be a real desert, leaving us feeling lost and parched. This research investigates the analgesic effects of a fixed-dose combination of orphenadrine and diclofenac (Neodolpasse) compared to its individual ingredients. The authors used a human pain model to measure the effects of these drugs on pain perception, finding that the combination was more effective than either ingredient alone. It's like combining the refreshing coolness of a desert spring with the nourishing power of a desert fruit – a potent combination for relieving pain!

Neodolpasse: A Synergistic Approach to Pain Relief

The study revealed that the combination of orphenadrine and diclofenac produced a significant reduction in pain perception, indicating that the two ingredients work synergistically to enhance pain relief. This finding suggests that combining these medications could be a more effective strategy for treating pain compared to using either drug alone. It's like a desert oasis, where different elements come together to create a haven of relief.

Managing Pain

Pain is a common experience, but finding the right treatment can be a challenge. This study emphasizes the importance of exploring different options and considering the potential benefits of combining medications. Remember, there's no one-size-fits-all approach to pain management, and finding the right combination for your needs can make a world of difference.

Dr. Camel's Conclusion

This research suggests that the combination of orphenadrine and diclofenac (Neodolpasse) can be an effective strategy for pain relief. It's a reminder that sometimes combining different approaches can lead to more potent and long-lasting results, just like a desert traveler might rely on a combination of resources to survive a challenging journey.

Date :
  1. Date Completed 2005-12-23
  2. Date Revised 2018-10-25
Further Info :

Pubmed ID

15991879

DOI: Digital Object Identifier

10.2165/00126839-200506040-00001

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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