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Treatment of ocular hypertension and open angle glaucoma: meta-analysis of randomised controlled trials.

Author: AntesGerd, Falck-YtterYngve T, FunkJens, MaierPhilip C, SchwarzerGuido

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Meta-analysis of trials showed that lowering intraocular pressure in patients with ocular hypertension or manifest glaucoma is beneficial in reducing the risk of visual field loss in the long term.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: Open angle glaucoma is one of the most common causes of blindness in industrialised nations. Treatments to lower ocular pressure are widely used in glaucoma prevention and treatment, despite conflicting evidence. DESIGN: We performed meta-analyses to reassess the effectiveness of pressur...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC558697/

データ提供：米国国立医学図書館（NLM）

Treatment of ocular hypertension and open angle glaucoma: meta-analysis of randomised controlled trials

This comprehensive meta-analysis examines the effectiveness of pressure-lowering treatments in preventing and treating open-angle glaucoma, a leading cause of blindness in industrialized nations. The researchers analyzed data from numerous randomized controlled trials, comparing pressure-lowering treatment to untreated control groups. The meta-analysis revealed a significant preventive effect of reducing intraocular pressure on the progression to glaucoma in patients with ocular hypertension. Additionally, the study found that lowering intraocular pressure in patients with manifest glaucoma significantly delayed visual field deterioration. This finding was particularly evident in patients with elevated pressure, while the effect was less pronounced in normal tension glaucoma. The researchers concluded that lowering intraocular pressure, both in individuals with ocular hypertension and those with manifest glaucoma, plays a crucial role in reducing the risk of visual field loss over the long term.

Lowering intraocular pressure: a key to managing glaucoma

The meta-analysis confirms the effectiveness of lowering intraocular pressure in delaying or preventing the progression of open-angle glaucoma. The study highlights the importance of early detection and intervention for individuals with ocular hypertension and those with manifest glaucoma.

Health implications and everyday applications

Individuals with ocular hypertension and open-angle glaucoma should consult with an ophthalmologist for regular eye exams and to discuss the potential benefits of pressure-lowering treatments. Early detection and treatment can significantly reduce the risk of vision loss.

Dr.Camel's Conclusion

Protecting our sight is crucial, and this study provides valuable insights into the importance of managing intraocular pressure for preventing and treating open-angle glaucoma. Early detection and timely intervention are key to preserving precious vision.

Date :
  1. Date Completed 2005-07-28
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

15994659

DOI: Digital Object Identifier

PMC558697

SNS
PICO Info
in preparation
Languages

English

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