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Comparison of L-hyoscyamine, glucagon, and placebo for air-contrast upper gastrointestinal series.

Author: DiPalmaJ A, GelorminiR, HughesJ J, ManganoF A, MoellerG, TomlinsonT L

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

L-hyoscyamine, an anticholinergic drug, is an effective and economical alternative to glucagon for hypotonic gastrointestinal radiography. In a study comparing the two medications, L-hyoscyamine provided images of equal quality to glucagon, with minimal side effects.
Paper Details　
Original Abstract of the Article :
Previous studies have compared the use of anticholinergic drugs and glucagon for upper gastrointestinal (UGI) radiography. Many radiologists prefer glucagon because these comparisons showed it to have a shorter duration of action with fewer side effects. L-Hyoscyamine is the levo-rotatory form of at...See full text at original site
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引用元：
https://doi.org/10.1007/BF01888546

データ提供：米国国立医学図書館（NLM）

A Comparative Study of Gastrointestinal Imaging Agents: L-Hyoscyamine vs. Glucagon

The field of medical imaging is a vast desert, with researchers constantly seeking new ways to illuminate the intricate details of the human body. This study, like a seasoned camel guide, navigates the landscape of upper gastrointestinal (UGI) radiography, comparing the effects of L-Hyoscyamine, glucagon, and placebo on gastric and duodenal distension, mucosal coating, and patient tolerance. The results suggest that L-Hyoscyamine, a drug with minor adverse effects, might be a valuable alternative to glucagon, offering comparable image quality with fewer side effects.

L-Hyoscyamine: A Cost-Effective Alternative in the Desert of Imaging

The study revealed that L-Hyoscyamine provided gastric and duodenal images equivalent to those obtained with glucagon. In the world of medical imaging, finding cost-effective alternatives is like discovering a well-spring in the desert. The researchers highlighted the potential of L-Hyoscyamine as a more economical option for hypotonic gastrointestinal radiography.

Navigating the Desert of Imaging: L-Hyoscyamine's Advantages and Considerations

This research provides a valuable tool for radiologists, allowing them to navigate the desert of UGI imaging with a cost-effective and comparable alternative to glucagon. However, it's important to remember that L-Hyoscyamine might cause dry mouth, a potential inconvenience similar to the occasional sandstorm encountered on a desert journey. As with any new journey, careful consideration and evaluation are crucial before embarking on this path.

Dr.Camel's Conclusion

This study, like a guidepost in the desert, points to L-Hyoscyamine as a potentially more economical and equally effective option for UGI radiography. It's a valuable addition to the toolkit of medical imaging, offering a cost-effective alternative in the ever-evolving landscape of medical technology.

Date :
  1. Date Completed 1992-07-29
  2. Date Revised 2019-10-21
Further Info :

Pubmed ID

1612300

DOI: Digital Object Identifier

10.1007/BF01888546

Related Literature

Article Analysis
・Side Effects of hyoscyamine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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