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Antibiotic prophylaxis following lower urinary tract instrumentation.

Author: BergmanA, BhatiaN N, EvansR P, KarramM M

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Cefadroxil was more effective in preventing postinstrumentation urinary tract infections than placebo and was better tolerated than nitrofurantoin in women undergoing lower urinary tract instrumentation.
Paper Details　
Original Abstract of the Article :
The value of routine antibiotic prophylaxis was assessed in 362 women undergoing lower urinary tract instrumentation. A three-day course of a once-a-day dose of 1 g of cefadroxil was compared with a three-day course of 100 mg of nitrofurantoin three times a day, in a randomized investigator blinded ...See full text at original site
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引用元：
https://doi.org/10.1016/0090-4295(92)90024-q

データ提供：米国国立医学図書館（NLM）

The Quest for Bladder Bliss: Antibiotic Prophylaxis After Lower Urinary Tract Instrumentation

In the realm of urology, preventing post-instrumentation urinary tract infections (UTIs) is a key goal. This study, like a thirsty traveler in a vast desert seeking an oasis of relief, explored the effectiveness of antibiotic prophylaxis in women undergoing lower urinary tract instrumentation. The researchers, armed with the tools of randomized, investigator-blinded, placebo-controlled studies, compared the efficacy of cefadroxil and nitrofurantoin against a placebo. They discovered that both study drugs significantly outperformed the placebo, proving their merit in preventing UTIs. While the two drugs exhibited comparable effectiveness, nitrofurantoin had a higher incidence of side effects, making cefadroxil the preferred choice due to its once-daily dosing schedule and favorable side effect profile. This research sheds light on the importance of antibiotic prophylaxis in preventing UTIs in this vulnerable population.

The Power of Prevention: Cefadroxil Emerges as the Champion

The study unveiled the efficacy of cefadroxil in preventing post-instrumentation UTIs. The results demonstrate that cefadroxil proves to be a formidable ally in the fight against UTIs, offering a favorable balance of effectiveness and tolerability. This finding underscores the significance of proactive measures in safeguarding patient health.

Navigating the Desert of UTIs: A Guide for Women

For women undergoing lower urinary tract instrumentation, this research offers a valuable insight. It's like finding a reliable compass in the vast desert of UTIs! Cefadroxil, with its once-daily dosing and favorable side effects, provides a dependable tool for preventing these infections. Remember, prevention is always better than cure, so stay hydrated and keep your bladder healthy!

Dr.Camel's Conclusion

The research provides valuable insights into the benefits of antibiotic prophylaxis in preventing UTIs following lower urinary tract instrumentation. Cefadroxil emerges as the preferred drug due to its effectiveness and favorable side effect profile. This research has the potential to improve patient outcomes and promote better bladder health.
Date :
  1. Date Completed 1992-07-28
  2. Date Revised 2019-07-13
Further Info :

Pubmed ID

1615615

DOI: Digital Object Identifier

10.1016/0090-4295(92)90024-q

Related Literature

Article Analysis
・Side Effects of cefadroxil
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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