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Pharmacokinetics and pharmacodynamics in clinical use of scopolamine.
Author: KirchWilhelm, OertelReinhard, RennerUlf D
Original Abstract of the Article :
The alkaloid L-(-)-scopolamine [L-(-)-hyoscine] competitively inhibits muscarinic receptors for acetylcholine and acts as a nonselective muscarinic antagonist, producing both peripheral antimuscarinic properties and central sedative, antiemetic, and amnestic effects. The parasympatholytic scopolamin...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1097/01.ftd.0000168293.48226.57
データ提供:米国国立医学図書館(NLM)
Scopolamine: A Pharmacological Journey Through the Desert of Muscarinic Inhibition
Scopolamine, an alkaloid with a long history in medicine, holds a unique position in the vast desert of pharmacology. This research provides a comprehensive review of scopolamine's pharmacokinetics and pharmacodynamics, exploring its various uses and effects. Scopolamine, known for its competitive inhibition of muscarinic receptors for acetylcholine, exhibits both peripheral antimuscarinic properties and central sedative, antiemetic, and amnestic effects. The researchers delve into the various dosage forms, routes of administration, and pharmacokinetic parameters associated with scopolamine. They discuss the drug's metabolism, renal excretion, and its interaction with other medications. This research provides a valuable resource for understanding the nuances of scopolamine's pharmacological profile.
Scopolamine: A Multifaceted Tool in Medicine
This review showcases the versatility of scopolamine in medicine, with applications ranging from premedication before anesthesia to motion sickness prevention. The researchers highlight the importance of considering the specific pharmacokinetic parameters and potential side effects associated with different dosage forms and routes of administration.
Navigating Scopolamine: A Reminder of Individual Needs
This review reminds us that each patient is unique, and the appropriate use of scopolamine must be tailored to individual needs. It's crucial to consult with a healthcare professional to determine the most suitable dosage form, route of administration, and potential risks and benefits.
Dr.Camel's Conclusion
This research offers a thorough and insightful exploration of the pharmacological profile of scopolamine. It provides a comprehensive understanding of its pharmacokinetics, pharmacodynamics, and clinical applications. Remember, navigating the vast desert of medication is best done with a guide, so consult with a healthcare professional to ensure safe and effective use of scopolamine.
Date :
- Date Completed 2006-01-04
- Date Revised 2022-04-08
Further Info :
Related Literature
English
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