Long-term follow-up after eradication of Helicobacter pylori with omeprazole, clarithromycin, and tinidazole (OCT regimen) in a Japanese population.

Author: AndoTakafumi, El-OmarEmad, GotoHidemi, InaKenji, IshiguroKazuhiro, KusugamiKazuo, MinamiMasaaki, MizunoTomokazu, NishiwakiTsuyoshi, NobataKazuo, ShimadaMasaaki, TsuzukiTomoyuki, WatanabeOsamu

Paper Details 
Original Abstract of the Article :
BACKGROUND: The long-term benefit of Helicobacter pylori eradication treatment that includes metronidazole on peptic ulcer disease in Japan is unclear. We investigated the rate of H. pylori re-infection and ulcer relapse after H. pylori eradication. MATERIALS AND METHODS: A total of 266 patients wi...See full text at original site
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引用元:
https://doi.org/10.1111/j.1523-5378.2005.00344.x

データ提供:米国国立医学図書館(NLM)

Eradicating Helicobacter pylori: A Long-Term Follow-Up Study in Japan

Helicobacter pylori infection is a common culprit behind peptic ulcer disease, and eradication therapy plays a crucial role in managing this condition. This study investigates the long-term outcomes of Helicobacter pylori eradication treatment using the omeprazole, clarithromycin, and tinidazole (OCT) regimen in a Japanese population. The researchers aimed to assess the rates of H. pylori re-infection and ulcer relapse over an extended period.

The study found that the OCT regimen achieved high eradication rates in the Japanese population, but it also revealed a significant re-infection rate. While ulcer relapse was relatively low, it was primarily associated with re-infection, highlighting the ongoing challenge of preventing reinfection. The study provides valuable insights into the long-term effectiveness of H. pylori eradication therapy in Japan, underscoring the need for strategies to reduce re-infection rates.

The Importance of Long-Term Monitoring and Prevention Strategies

This study emphasizes the importance of long-term monitoring and proactive measures to prevent re-infection after successful H. pylori eradication. The researchers' findings highlight the need for individualized strategies to address the unique challenges of re-infection in specific populations, such as those in Japan.

A Journey Beyond Eradication: Managing H. pylori Re-infection

The fight against H. pylori infection is a long-term journey that extends beyond eradication. This study underscores the need for continued vigilance and effective strategies to manage re-infection and prevent the recurrence of peptic ulcer disease.

Dr. Camel's Conclusion

Just as a desert oasis can be a fleeting mirage, H. pylori eradication can be a temporary victory. This study emphasizes the importance of staying vigilant, recognizing that re-infection is a real possibility. By developing targeted strategies for preventing re-infection, we can better manage H. pylori infection and improve the long-term health of those affected.

Date :
  1. Date Completed 2005-11-15
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

16181347

DOI: Digital Object Identifier

10.1111/j.1523-5378.2005.00344.x

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PICO Info
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Languages

English

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