Effects of omeprazole clarithromycin: A Synthesis of Findings from 29 Studies

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Original Abstract of the Article

Major research findings

This study investigated the efficacy of oral olopatadine for preventing nasal allergy symptoms, particularly nasal congestion, in patients with seasonal allergic rhinitis (SAR) caused by Japanese cedar pollen (SAR-JP). A randomized, double-blind, placebo-controlled study was conducted involving 110 patients with SAR-JP. 1 . The results showed that oral olopatadine significantly reduced sneezing, rhinorrhea, and nasal congestion. Furthermore, the olopatadine group had a better overall quality of life (QOL) score during the peak cedar pollen season compared to the placebo group (p < 0.05), with notable improvements in QOL scores related to daily activities and outdoor activities.

Benefits and Risks

Benefit Summary

Oral olopatadine may be an effective treatment for nasal allergy symptoms, such as sneezing, runny nose, and nasal congestion, in individuals with SAR-JP. 1 . Additionally, it has the potential to improve QOL, particularly in areas related to daily activities and outdoor activities.

Risk Summary

No serious adverse effects were reported during the study period associated with oral olopatadine treatment. 1 .

Comparison Across Studies

Research Similarities

This research aligns with other studies in indicating the potential effectiveness of olopatadine in alleviating nasal allergy symptoms. The safety profile of olopatadine as a treatment option is also consistent across various studies.

Research Differences

Direct comparisons between studies are difficult due to variations in participant populations, study designs, and assessment methods.

Consistency and Contradictions in Results

This research supports the potential benefits of oral olopatadine in managing SAR-JP. However, further investigation is needed to confirm its long-term effects, its effectiveness against other types of allergies, and its comparative efficacy against other available treatments.

Applying the Findings to Everyday Life: Considerations

While oral olopatadine shows promise for alleviating SAR-JP symptoms, it's important to remember that individual responses may vary. Consultation with a healthcare professional is crucial before starting any new treatment, to assess individual needs and potential risks.

Limitations of the Current Study

The study had a relatively small sample size and focused specifically on SAR-JP. Generalizing the findings to other types of allergies or broader populations requires further investigation.

Future Research Directions

Larger-scale studies are needed to confirm and expand upon the findings regarding the effectiveness of oral olopatadine. Research exploring its efficacy against other pollen allergies, its long-term impact, and its comparative effectiveness against alternative treatments would be valuable.

Conclusion

This study suggests that oral olopatadine may be a valuable treatment option for individuals experiencing SAR-JP. However, further research is warranted. Consult with a healthcare professional before starting any new treatment to determine if it's appropriate for your specific needs.

Keywords
Benefit Keywords
Improved quality of life
1
H. pylori eradication
Safe treatment
2
Gastric emptying improvement
3
Reduced ulcer recurrence
4
H. pylori eradication
5
Improved cognitive function
Improved functional status
6
Effective H. pylori eradication
H. pylori eradication
Shorter treatment duration
shorter treatment duration
7
Long-term safety
8
Effective for H. pylori
Eradication therapy
9
H. pylori eradication
10
H. pylori eradication
11
Short-term inflammation decrease
12
H. pylori eradication
13
H. pylori eradication
14
H. pylori eradication
15
H. pylori eradication
16
Acid stable and soluble
Acid stable drug
Effective H. pylori treatment
Effective against H. pylori
Effective treatment for H. pylori infection
Eradicate H. pylori infection
Eradication of H. pylori
Eradication of infection
H. pylori eradication
17
Effective H. pylori treatment
18
Treats H. pylori infection
19
Hp infection eradication
20
H. pylori eradication
Prevents ulcer recurrence
Ulcer prevention
Ulcer recurrence prevention
prevents ulcer recurrence
21
H. pylori treatment
Improved patient outcomes
Pain relief
22
Effective H. pylori eradication
H. pylori eradication
effective regimen
23
Eradication efficacy
24
H. pylori eradication
25
H. pylori eradication
26
H. pylori eradication
27
Effective H. pylori eradication
H. pylori eradication
effective regimen
28
H. pylori eradication
29
Risk Keywords
Diarrhea
Liver function changes
Metronidazole resistance
2
Short-term dysbiosis
8
Resistance
Side-effects
9
Mild side effects
10
Antibacterial treatment not recommended
Gastritis worsening
No long-term effect
12
Side effects
13
Adverse events
Reduced eradication rate
14
H. pylori re-infection
Ulcer relapse
15
Penicillin allergy
16
Antibiotic resistance
18
Adverse effects of drugs
19
5-nitroimidazole resistance
Antibiotic resistance
Metronidazole resistance
23
Eradication failure
24
Antibiotic resistance
25
Side effects
27
5-nitroimidazole resistance
Antibiotic resistance
Metronidazole resistance
28
Literature analysis of 29 papers
Positive Content
28
Neutral Content
0
Negative Content
1
Article Type
9
0
0
3
28
1.

Efficacy of oral olopatadine hydrochloride for the treatment of seasonal allergic rhinitis: A randomized, double-blind, placebo-controlled study.

Author: YamamotoHideyuki, YamadaTakechiyo, KuboSeita, OsawaYoko, KimuraYuichi, OhMyonmi, SusukiDai, TakabayashiTetsuji, OkamotoMasayuki, FujiedaShigeharu

Improved quality of life

Oral olopatadine effectively controlled nasal allergy symptoms in patients with seasonal allergic rhinitis, particularly nasal congestion. It also improved quality of life and had no significant adverse effects.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

2.

Eradication of Helicobacter pylori with lansoprazole, roxithromycin and metronidazole--an open pilot study.

Author: PohleT, StollR, KirchnerT, HeepM, LehnN, BockH, DomschkeW

H. pylori eradication
Safe treatment
Diarrhea
Liver function changes
Metronidazole resistance

The combination of lansoprazole, roxithromycin and metronidazole proved to be as safe as other current triple therapy regimens. In a study of 163 patients with duodenal ulcer and proven H. pylori infection, H. pylori was successfully eradicated in 84.7% of cases as determined by urease quick test, 78.0% by histology, 81.3% by 13C-urea breath test; and in 75.3%, at least two tests were negative.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

4.

[Effects of Helicobacter pylori eradication on the recurrence of gastric ulcer during a 12-month follow up].

Author: BermejoF, BoixedaD, GisbertJ P, DefargesV, Martín de ArgilaC, SanzJ M, García PlazaA

Reduced ulcer recurrence

Helicobacter pylori eradication dramatically reduces gastric ulcer recurrence. In a study of 73 patients, the cumulative ulcer recurrence rate was 2.3% in those with successful eradication compared to 70% in those with eradication failure.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Spanish

5.

Smoking and drinking habits are important predictors of Helicobacter pylori eradication.

Author: NamiotD B, LeszczyńskaK, NamiotZ, KurylonekA J, KemonaA

H. pylori eradication

Smoking significantly decreased the efficacy of H. pylori eradication in certain therapeutic groups, particularly when combined with non-drinking habits. Drinking did not affect eradication efficacy.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

6.

Eradication of Helicobacter pylori may be beneficial in the management of Alzheimer's disease.

Author: KountourasJannis, BozikiMarina, GavalasEmmanuel, ZavosChristos, GrigoriadisNikolaos, DeretziGeorgia, TzilvesDimitrios, KatsinelosPanagiotis, TsolakiMagda, ChatzopoulosDimitrios, VenizelosIoannis

Improved cognitive function
Improved functional status

This study found a strong link between Helicobacter pylori (Hp) infection and Alzheimer's disease (AD), suggesting that eradicating Hp may improve cognitive and functional abilities in AD patients.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

7.

[Omeprazole plus 2 antibiotics for the eradication of H. pylori, are 5 days of treatment sufficient?].

Author: GisbertJ P, BoixedaD, BermejoF, MorenoL, RamosF, Martín de ArgilaC, García ArataI, García PlazaA

Effective H. pylori eradication
H. pylori eradication
Shorter treatment duration
shorter treatment duration

Five-day H. pylori treatment with omeprazole, metronidazole, and clarithromycin or amoxicillin is being investigated as a shorter alternative to the standard 7-day course.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : Spanish

8.

Long-term changes in the gut microbiota after 14-day bismuth quadruple therapy in penicillin-allergic children.

Author: ZhouYing, YeZiqing, LuJunping, MiaoShijian, LuXiaolan, SunHua, WuJie, WangYuhuan, HuangYing

Long-term safety
Short-term dysbiosis

Bismuth quadruple therapy for Helicobacter pylori infection in penicillin-allergic children caused short-term dysbiosis of the gut microbiota. Most changes recovered within one year, indicating the long-term safety of this treatment.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

10.

[Seven-day omeprazole, clarithromycin, and amoxicillin for the therapy of Helicobacter pylori infection].

Author: CometR, CalvetX, NavarroM, GarcíaN, SanfeliuI

H. pylori eradication
Mild side effects

Seven-day therapy with omeprazole, amoxicillin and clarithromycin achieved an 85% cure rate of H. pylori infection in patients with peptic ulcer disease.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Spanish

11.

Effectiveness of two quadruple, tetracycline- or clarithromycin-containing, second-line, Helicobacter pylori eradication therapies.

Author: GeorgopoulosS D, LadasS D, KaratapanisS, TriantafyllouK, SpiliadiC, MentisA, ArtikisV, RaptisS A

H. pylori eradication

Tetracycline-containing quadruple therapy is highly effective in treating Helicobacter pylori eradication failures following omeprazole-clarithromycin-amoxicillin triple therapy. In a study of 95 patients, eradication rates were 84% in the tetracycline group and 59% in the clarithromycin group.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

13.

Third-line rescue therapy with levofloxacin is more effective than rifabutin rescue regimen after two Helicobacter pylori treatment failures.

Author: GisbertJ P, GisbertJ L, MarcosS, Moreno-OteroR, PajaresJ M

H. pylori eradication
Side effects

A 10-day triple levofloxacin-based rescue regimen was more effective than the same regimen with rifabutin in treating Helicobacter pylori eradication failures.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

14.

The effectiveness of omeprazole, clarithromycin and tinidazole in eradicating Helicobacter pylori in a community screen and treat programme. Leeds Help Study Group.

Author: MoayyediP, FeltbowerR, CrocombeW, MasonS, AthaP, BrownJ, DowellA C, RichardsI D, AxonA T

H. pylori eradication
Adverse events
Reduced eradication rate

The eradication rate of H. pylori was 61% in an intention-to-treat analysis, which is less successful than hospital studies in dyspeptic patients. Adverse events occurred in 45% of the treatment group.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

15.

Long-term follow-up after eradication of Helicobacter pylori with omeprazole, clarithromycin, and tinidazole (OCT regimen) in a Japanese population.

Author: AndoTakafumi, MinamiMasaaki, MizunoTomokazu, WatanabeOsamu, IshiguroKazuhiro, InaKenji, KusugamiKazuo, NobataKazuo, NishiwakiTsuyoshi, TsuzukiTomoyuki, ShimadaMasaaki, El-OmarEmad, GotoHidemi

H. pylori eradication
H. pylori re-infection
Ulcer relapse

This study found that triple therapy with omeprazole, clarithromycin, and tinidazole is useful for Helicobacter pylori eradication in Japan, but there is an appreciable re-infection rate in this population.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

16.

Helicobacter pylori first-line and rescue treatments in the presence of penicillin allergy.

Author: GisbertJavier P, BarrioJesús, ModolellInés, Molina-InfanteJavier, AisaAngeles Perez, Castro-FernándezManuel, RodrigoLuis, CosmeAngel, GisbertJose Luis, Fernández-BermejoMiguel, MarcosSantiago, MarínAlicia C, McNichollAdrián G

H. pylori eradication
Penicillin allergy

In patients allergic to penicillin, a first-line treatment with a bismuth-containing quadruple therapy seems to be a better option than the triple PPI-clarithromycin-metronidazole regimen.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Language : English

18.

Beta-lactamase inhibitor enhances Helicobacter pylori eradication rate.

Author: OjettiV, MignecoA, ZoccoM A, NistaE C, GasbarriniG, GasbarriniA

Effective H. pylori treatment
Antibiotic resistance

One-week triple therapy, the standard treatment for Helicobacter pylori infection, often faces challenges due to increasing resistance. This study highlights the potential advantages of amoxicillin-clavulanate combination over amoxicillin alone and explores the 'in-vitro' antibacterial activity of beta-lactamase inhibitors against H. pylori.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

19.

A randomized trial comparing four Helicobacter pylori eradication regimens: standard triple therapy, ciprofloxacin based triple therapy, quadruple and sequential therapy.

Author: AminianKeyvan, FarsadFaraneh, GhanbariAtefeh, FakhreihSaba, HasheminasabSayed Mohammad

Treats H. pylori infection
Adverse effects of drugs

Standard 10 days triple therapy had the highest success rate in eradicating H. pylori infection in our study. Quadruple therapy was the second successful regimen.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

20.

[Methods to optimize the management of Helicobacter pylori infection. The comparative efficacy of the triple and quadruple therapy used as a first line therapy].

Author: Grigor'evP Ia, IakovenkoA V, IakovenkoE P, Vasil'evI V, KomlevaIu V, OprishchenkoI V, AldiiarovaM A

Hp infection eradication

This study compared the efficacy of triple and quadruple therapies for eradication of Helicobacter pylori infection over a 5-year period. The study found that the quadruple therapy was more effective than the triple therapy.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Russian

21.

Pooled analysis of anti-Helicobacter pylori treatment regimens.

Author: UngeP, BerstadA

H. pylori eradication
Prevents ulcer recurrence
Ulcer prevention
Ulcer recurrence prevention
prevents ulcer recurrence

H. pylori infection and peptic ulcers can be effectively treated, which helps prevent ulcer recurrence.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

22.

Pharmacist-managed Helicobacter pylori clinic.

Author: MorrealeA P

H. pylori treatment
Improved patient outcomes
Pain relief

A pharmacist-managed clinic effectively assessed and treated Helicobacter pylori infection in patients using long-term acid-suppressing medications.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

23.

Relevance of antibiotic sensitivities in predicting failure of omeprazole, clarithromycin, and tinidazole to eradicate Helicobacter pylori.

Author: MoayyediP, RagunathanP L, MapstoneN, AxonA T, TompkinsD S

Effective H. pylori eradication
H. pylori eradication
effective regimen
5-nitroimidazole resistance
Antibiotic resistance
Metronidazole resistance

The OCT regimen (omeprazole, clarithromycin, and tinidazole) was effective for H. pylori eradication (89%). Metronidazole resistance, assessed by E-test, may predict treatment failure, but disc diffusion technique is not useful for prediction.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

24.

Third-line rescue therapy with levofloxacin after two H. pylori treatment failures.

Author: GisbertJavier P, Castro-FernándezManuel, BermejoFernando, Pérez-AisaAngeles, DuconsJulio, Fernández-BermejoMiguel, BoryFelipe, CosmeAngel, BenitoLuis-Miguel, López-RivasLaureano, LamasEloisa, PabónManuel, OlivaresDavid,

Eradication efficacy
Eradication failure

A third-line treatment with levofloxacin is being evaluated for patients with two failed attempts to eradicate Helicobacter pylori, a bacteria that can cause stomach ulcers. This study aims to assess the efficacy and safety of this treatment option.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

25.

Macrolide resistance in the normal microbiota after Helicobacter pylori treatment.

Author: JakobssonHedvig, WreiberKarin, FallKatja, FjelstadBjörn, NyrénOlof, EngstrandLars

H. pylori eradication
Antibiotic resistance

Triple therapy for H. pylori eradication using clarithromycin can lead to persistent macrolide resistance in the normal microbiota, raising concerns about antibiotic resistance.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

26.

Randomized controlled comparison of nitroimidazoles for the eradication of Helicobacter pylori and relief of ulcer-associated and non-ulcer dyspepsia.

Author: GoddardA F, LoganR P, LawesS, SpillerR C

H. pylori eradication

Treatment with omeprazole, clarithromycin, and metronidazole (OCM) is as effective as the more expensive tinidazole regimen (OCT) at eradicating Helicobacter pylori. H. pylori eradication results in long-term relief of dyspeptic symptoms and reduced antisecretory consumption only in patients with duodenal ulcer, and not in those with non-ulcer dyspepsia.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

27.

Omeprazole-based antimicrobial therapies: results in 198 Helicobacter pylori-positive patients.

Author: DeltenreM, JonasC, van GossumM, BusetM, OteroJ, De KosterE

H. pylori eradication
Side effects

Clarithromycin-based therapies were significantly more effective at eradicating Helicobacter pylori infection than amoxycillin-based therapies.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

29.

A randomized controlled comparison of three quadruple therapy regimens in a population with low Helicobacter pylori eradication rates.

Author: SotudehmaneshR, MalekzadehR, FazelA, MassarratS, Ziad-AlizadehB, EshraghianM R

H. pylori eradication

This study compared the efficacy and tolerability of omeprazole/clarithromycin/bismuth/tetracycline-based quadruple therapy to that of ranitidine/metronidazole/bismuth/tetracycline-based quadruple therapy in patients with high prevalence of metronidazole-resistant Helicobacter pylori.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

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