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Efficacy of oral naratriptan in the treatment of menstrually related migraine.

Author: , Bidaut-MazelC, HinzelinG, JaminC, MassiouH

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Oral naratriptan (2.5 mg) was effective in the acute treatment of menstrually related migraine, with significant pain relief observed as early as 2 hours after treatment.
Paper Details　
Original Abstract of the Article :
The aim of this study was to investigate the efficacy of orally administered 2.5 mg naratriptan in the treatment of menstrually related migraine (MRM). A high percentage of women suffering from migraine report increased frequency of attacks in association with menstruation that may be more severe, o...See full text at original site
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引用元：
https://doi.org/10.1111/j.1468-1331.2005.01076.x

データ提供：米国国立医学図書館（NLM）

Oral Naratriptan for the Treatment of Menstrually Related Migraine

Navigating the complexities of migraine treatment is like traversing a vast desert, where each patient's experience is unique and requires tailored solutions. This research focuses on a specific subset of migraine sufferers: those who experience heightened symptoms during their menstrual cycle. The study investigates the efficacy of orally administered naratriptan, a triptan medication, in alleviating the pain and associated symptoms of menstrually related migraine (MRM).

Naratriptan Demonstrates Efficacy in Treating Menstrually Related Migraine

This phase IIIb clinical trial provides robust evidence for the effectiveness of naratriptan in treating MRM. The study found that a significantly higher percentage of patients who received naratriptan experienced complete pain relief compared to those who received placebo. Naratriptan also demonstrated improvements in other secondary measures, such as sustained pain-free response, absence of associated symptoms, and overall patient satisfaction.

Relief for Menstrually Related Migraine Sufferers

This research offers hope for individuals who struggle with MRM, providing a potential treatment option for this debilitating condition. The findings suggest that naratriptan may effectively alleviate the pain and associated symptoms of MRM, improving quality of life for those affected. As we continue to explore the desert of migraine research, we are gaining valuable insights into the unique needs of different migraine subtypes and discovering new treatment options to alleviate suffering.

Dr. Camel's Conclusion

This study is a welcome oasis in the desert of migraine research, providing a potential treatment option for individuals experiencing menstrually related migraine. The effectiveness of naratriptan in alleviating pain and associated symptoms offers hope for improved quality of life for those affected. We must continue to journey through this desert, seeking to understand the complex mechanisms underlying migraine and developing innovative treatments to address its diverse manifestations.

Date :
  1. Date Completed 2006-01-17
  2. Date Revised 2016-11-24
Further Info :

Pubmed ID

16190915

DOI: Digital Object Identifier

10.1111/j.1468-1331.2005.01076.x

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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