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Randomized controlled trial of pulse intravenous cyclophosphamide versus mycophenolate mofetil in the induction therapy of proliferative lupus nephritis.
Author: AhmadGhazali, GhazalliRozina, GohBak Leong, HooiLai Seong, LimTeck Onn, MoradZaki, OngLoke Meng, ShaariahWan, TanChwee Choon, TanSi Yen, TeoSue Mei, WongHin Seng
Original Abstract of the Article :
BACKGROUND: The aim of the present study was to evaluate the efficacy of mycophenolate mofetil in the induction therapy of proliferative lupus nephritis. METHODS: Forty-four patients from eight centres with newly diagnosed lupus nephritis World Health Organization class III or IV were randomly assi...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/j.1440-1797.2005.00444.x
データ提供:米国国立医学図書館(NLM)
Lupus Nephritis: A Comparative Study of Treatment Options
Lupus nephritis, a serious complication of systemic lupus erythematosus, can lead to kidney damage and even kidney failure. The quest for effective treatment options continues, with researchers exploring different medications to manage this complex condition. This study aimed to compare the efficacy of two medications, mycophenolate mofetil (MMF) and intravenous cyclophosphamide (IVC), in the induction therapy of proliferative lupus nephritis. The researchers conducted a randomized controlled trial involving 44 patients with newly diagnosed lupus nephritis, analyzing the effectiveness of each medication in achieving remission and improving renal function. The results showed that both MMF and IVC were effective in achieving remission, with similar improvements in various clinical markers.
Navigating the Complexities of Lupus Nephritis: Finding Effective Treatment Options
The study's findings, like a compass guiding us through the intricate pathways of lupus nephritis, offer valuable insights into the effectiveness of different treatment options. The researchers discovered that both MMF and IVC are effective in achieving remission and improving renal function, suggesting that healthcare professionals have more than one viable option for managing this complex condition. This knowledge empowers healthcare professionals to make informed decisions about treatment strategies based on individual patient characteristics and preferences.
Lupus Nephritis: Understanding the Treatment Landscape
Lupus nephritis can significantly impact the quality of life for individuals with systemic lupus erythematosus. This study provides valuable information for healthcare professionals and patients navigating the complex treatment landscape. The findings highlight the effectiveness of both MMF and IVC in achieving remission and improving renal function, offering hope for a brighter future for individuals with lupus nephritis.
Dr. Camel's Conclusion
This study, like a wellspring of knowledge in the desert of lupus nephritis, offers valuable insights into the effectiveness of different treatment options. The researchers discovered that both MMF and IVC are effective in achieving remission and improving renal function, offering a beacon of hope for those battling this complex condition. The findings serve as a valuable roadmap for healthcare professionals, enabling them to make informed decisions and guide patients towards a healthier future.
Date :
- Date Completed 2005-12-15
- Date Revised 2022-03-17
Further Info :
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