The use and safety profile of non-steroidal antiinflammatory drugs among Turkish patients with osteoarthritis.

Author: GürelSelim, OzdemirOktay, YilmazHürriyet

Paper Details 
Original Abstract of the Article :
BACKGROUND/AIMS: To determine the use and safety profile of non-steroidal anti-inflammatory drugs (NSAIDs) among Turkish osteoarthritis patients. METHODS: Osteoarthritis patients were interviewed by 138 doctors from clinics in nine different cities. Doctors completed a questionnaire regarding non-s...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/16245223

データ提供:米国国立医学図書館(NLM)

Non-steroidal Anti-inflammatory Drugs (NSAIDs) for Osteoarthritis

This research delves into the [use and safety profile] of [non-steroidal anti-inflammatory drugs (NSAIDs)] in patients with [osteoarthritis]. The study analyzed data from [3,755 patients] with [osteoarthritis] in [Turkey] to assess the [prevalence of NSAID use] and the [incidence of side effects].

Prevalence and Side Effects of NSAIDs

The study found that [meloxicam and specific cyclooxygenase-2 (COX-2) inhibitors, such as celecoxib and rofecoxib], were among the most commonly used NSAIDs. The most frequent side effects reported were [epigastric burning, dyspeptic symptoms, abdominal pain, constipation, nausea, and diarrhea]. Interestingly, [COX-2 selective inhibitors] were associated with [significantly lower incidence of dyspeptic complaints] compared to [non-selective NSAIDs].

Balancing Benefits and Risks of NSAIDs

This research highlights the [important considerations] involved in [NSAID use for osteoarthritis]. While [NSAIDs] can provide [significant pain relief], it's crucial to be aware of their [potential side effects] and to consult with a healthcare professional to determine the most appropriate treatment approach. The study suggests that [COX-2 selective inhibitors] may offer a [more favorable] side effect profile for some patients.

Dr. Camel's Conclusion

This research reminds us that the desert of osteoarthritis treatment can be a complex and often challenging journey. While [NSAIDs] can provide relief, it's crucial to carefully weigh the benefits and risks of these medications. This study offers valuable insights into the [prevalence and side effects of NSAIDs] and underscores the importance of [individualized treatment plans] to ensure optimal outcomes for patients with osteoarthritis.

Date :
  1. Date Completed 2007-08-24
  2. Date Revised 2022-04-19
Further Info :

Pubmed ID

16245223

DOI: Digital Object Identifier

16245223

Related Literature

SNS
PICO Info
in preparation
Languages

English

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