Intravenous use of the calcium-channel blocker nicardipine as second-line treatment in severe, early-onset pre-eclamptic patients.

Author: BartelsPieter A, BijvankBas Nij, HanffLidwien M, RoofthooftDaniella W E, SteegersEric A P, VisserWilly, VultoArnold G

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To evaluate the efficacy of intravenous administration of nicardipine as a second-line temporizing treatment in severe, early-onset, pre-eclamptic patients. DESIGN: An open, prospective, evaluation study. SETTING: A high-care obstetric ward in a tertiary care centre. PATIENTS: Twenty-s...See full text at original site
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引用元:
https://doi.org/10.1097/01.hjh.0000188729.73807.16

データ提供:米国国立医学図書館(NLM)

Nicardipine for Severe, Early-Onset Pre-eclampsia: A Second-Line Treatment Option

The field of obstetrics is always seeking to provide the best possible care for pregnant women and their babies. Pre-eclampsia, a serious pregnancy complication characterized by high blood pressure and other symptoms, can pose a significant risk to both mother and child. This study explores the efficacy of nicardipine, a calcium-channel blocker, as a second-line treatment for severe, early-onset pre-eclampsia in cases where standard antihypertensive medications have failed.

The researchers conducted a prospective study of pregnant women with severe, early-onset pre-eclampsia. The women received nicardipine infusion after failing to respond to other antihypertensive medications. The study aimed to evaluate the effectiveness of nicardipine in controlling blood pressure and prolonging pregnancy. The findings of this study provide valuable insights into the potential benefits and safety of nicardipine in treating severe pre-eclampsia.

Nicardipine: A Potential Solution for Severe Pre-eclampsia

This study demonstrates the potential effectiveness of nicardipine as a second-line treatment for severe, early-onset pre-eclampsia. The researchers found that nicardipine effectively controlled blood pressure and allowed for a significant prolongation of pregnancy. This research highlights the importance of having a range of treatment options available for managing this complex and potentially life-threatening condition.

Managing Pre-eclampsia: A Team Approach

This research underscores the importance of a multidisciplinary approach to managing pre-eclampsia. The study highlights the need for a range of treatment options, including second-line medications like nicardipine, to effectively control blood pressure and improve patient outcomes. This research emphasizes the collaborative efforts of obstetricians, neonatologists, and other healthcare professionals in ensuring the best possible care for pregnant women with pre-eclampsia.

Dr. Camel's Conclusion

Think of a pregnant woman with severe pre-eclampsia as a camel caravan facing a fierce sandstorm. Standard antihypertensive medications, like a trusty camel's guide, may not be enough to weather the storm. This study suggests that nicardipine, like a sturdy camel's pack, can provide additional protection, helping to control blood pressure and ensure a safe journey for both mother and child.

Date :
  1. Date Completed 2006-03-02
  2. Date Revised 2019-08-23
Further Info :

Pubmed ID

16269975

DOI: Digital Object Identifier

10.1097/01.hjh.0000188729.73807.16

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SNS
PICO Info
in preparation
Languages

English

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