Major research findings

Nicardipine is an effective drug for the treatment of severe hypertension in pregnancy and may be a better alternative to other available treatment options. 10 . Nicardipine achieved a significant reduction in both diastolic and systolic blood pressure in pregnant patients with severe hypertension. 10 . Nicardipine can be used as an alternative treatment in patients with severe early-onset preeclampsia when standard intravenous antihypertensive drugs (ketanserin, dihydralazine, or labetalol) have failed. 19 . Nicardipine has been shown to have fewer side effects compared to other drugs in patients at risk of preterm labor. . Nicardipine has been shown to have fewer side effects compared to other drugs in patients at risk of preterm labor. . Nicardipine has been shown to have fewer side effects such as nausea, dizziness, and lightheadedness when administered orally compared to other drugs. 1 . Nicardipine can be used to lower blood pressure in newborns. 26 . However, nicardipine can cause pulmonary edema in pregnant patients. 18 . Nicardipine can cause pulmonary edema in pregnant patients. 17 . Nicardipine can cause pulmonary edema in pregnant patients. 21 .

Reasons for side effects

Nicardipine is one of a class of drugs called calcium channel blockers. Calcium channel blockers lower blood pressure by blocking calcium from entering the cells of the heart and blood vessel muscles. 24 . The side effects of nicardipine are due to this calcium channel blocking effect.

Common side effects

Dizziness

Nicardipine can cause dizziness by lowering blood pressure. 1 . Dizziness is more likely to occur when you first start taking the drug or when you increase your dose. 1 . If you feel dizzy, you should be careful when getting up from a sitting or lying position.

Headache

Nicardipine can cause headache. 1 . If you have a severe headache, you should talk to your doctor.

Lightheadedness

Nicardipine can cause lightheadedness. 1 . If you feel lightheaded, you should be careful when getting up from a sitting or lying position.

Palpitations

Nicardipine can cause palpitations. 1 . If you have palpitations, you should talk to your doctor.

Edema

Nicardipine can cause edema. 1 . If you have severe edema, you should talk to your doctor.

Hypotension

Nicardipine can cause hypotension. 9 . Hypotension can cause symptoms such as dizziness, lightheadedness, and fainting. 9 . If you are concerned about hypotension, you should talk to your doctor.

Pulmonary edema

Nicardipine can cause pulmonary edema. 18 . Pulmonary edema is a condition where fluid builds up in the lungs. 18 . Symptoms of pulmonary edema include shortness of breath, coughing, and difficulty breathing. 18 . If you suspect pulmonary edema, you should see a doctor immediately.

Measures against side effects

Dizziness

If you feel dizzy, you should be careful when getting up from a sitting or lying position. 1 . You should also talk to your doctor if you feel dizzy.

Headache

If you have a severe headache, you should talk to your doctor. 1 .

Lightheadedness

If you feel lightheaded, you should be careful when getting up from a sitting or lying position. 1 . You should also talk to your doctor if you feel lightheaded.

Palpitations

If you have palpitations, you should talk to your doctor. 1 .

Edema

If you have severe edema, you should talk to your doctor. 1 .

Hypotension

If you are concerned about hypotension, you should talk to your doctor. 9 .

Pulmonary edema

If you suspect pulmonary edema, you should see a doctor immediately. 18 .

Comparison between studies

Commonalities

These studies show that nicardipine is effective in treating hypertension in pregnancy. 10 . These studies also show that nicardipine has fewer side effects than other drugs in pregnant patients. .

Differences

These studies differ in the route of administration and dosage of nicardipine, as well as the type and severity of side effects. 10 . For example, one study shows that nicardipine is effective when administered orally. 1 . Another study shows that nicardipine is effective when administered intravenously. 19 .

Cautions for practical application

Nicardipine is an effective drug for the treatment of hypertension in pregnancy, but it is important to remember that there is a risk of side effects. 10 . When taking nicardipine, you should follow your doctor's instructions carefully and talk to your doctor immediately if you experience any side effects. 10 . Nicardipine may also interact with other medications. 10 . Therefore, when taking nicardipine, you should tell your doctor about all medications you are currently taking. 10 .

Limitations of current research

Research on the side effects of nicardipine is still insufficient. 10 . In particular, little is known about the long-term effects of nicardipine in pregnant patients. 10 .

Future research directions

Further research is needed on the side effects of nicardipine. 10 . In particular, it is necessary to investigate the long-term effects of nicardipine in pregnant patients. 10 . Research is also needed to optimize the route of administration and dosage of nicardipine. 10 .

Conclusion

Nicardipine is an effective drug for the treatment of hypertension in pregnancy and may be a better alternative to other available treatment options. 10 . However, it is important to remember that nicardipine has a risk of side effects. 10 . When taking nicardipine, you should follow your doctor's instructions carefully and talk to your doctor immediately if you experience any side effects. 10 .