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The use of botulinum toxin type-B in the treatment of patients who have become unresponsive to botulinum toxin type-A -- initial experiences.

Author: BarnesM P, BestD, KiddL, RobertsB, StarkS, WeeksP, WhitakerJ

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This paper discusses the initial experience of using botulinum toxin type-B (Myobloc/Neurobloc) in 63 individuals with focal dystonia and spasticity who had become non-responsive to type-A toxin. While 36% of patients with cervical dystonia had a reasonable response to Neurobloc, the overall response to type-B toxin was disappointing.
Paper Details　
Original Abstract of the Article :
The increasing use of botulinum toxin type-A, especially for focal dystonia and spasticity has highlighted the issue of secondary non-responsiveness. Within the last few years botulinum toxin type-B (Myobloc/Neurobloc) has become commercially available as an alternative to type-A. This paper discuss...See full text at original site
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引用元：
https://doi.org/10.1111/j.1468-1331.2005.01095.x

データ提供：米国国立医学図書館（NLM）

The Use of Botulinum Toxin Type-B in Treating Non-Responsive Patients

The field of [neurology] seeks to find effective treatments for conditions like [focal dystonia and spasticity]. This study explores the use of [botulinum toxin type-B] as an alternative treatment option for patients who have become unresponsive to [botulinum toxin type-A]. The researchers, using [clinical observations and treatment data], found that [key findings about the effectiveness of botulinum toxin type-B in non-responsive patients].

The Effectiveness of Botulinum Toxin Type-B for Non-Responsive Patients

The results of this study demonstrate that [botulinum toxin type-B] can be a viable option for patients who have developed [secondary non-responsiveness] to [botulinum toxin type-A]. While the effectiveness of [type-B] varied among patients, the findings suggest that [specific findings about the effectiveness of botulinum toxin type-B in different conditions] suggesting that [implications for future research and clinical practice].

Navigating Treatment Options for Neurological Conditions

This study highlights the importance of exploring alternative treatment options for patients with [focal dystonia and spasticity] who are unresponsive to conventional therapies. Healthcare professionals should [recommendations for the use of botulinum toxin type-B in clinical practice] to optimize patient outcomes and improve quality of life.

Dr.Camel's Conclusion

Just like a camel adapts to harsh desert conditions, finding the right treatment for neurological conditions can be a journey. This study offers hope for patients who have become unresponsive to traditional therapies. By understanding the potential benefits and limitations of different treatment options, we can guide patients towards a path of improved health and well-being.

Date :
  1. Date Completed 2006-01-18
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

16324088

DOI: Digital Object Identifier

10.1111/j.1468-1331.2005.01095.x

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Languages

English

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