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The role of photochemical treatment with amotosalen and UV-A light in the prevention of transfusion-transmitted cytomegalovirus infections.

Author: ConlanMaureen, DrewW Lawrence, LjungmanPer, NicholsW Garrett, PreiksaitisJutta K, RobackJohn D

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review discusses the use of photochemical treatment (PCT) to inactivate cytomegalovirus (CMV) in platelet concentrates. PCT has been shown to effectively reduce CMV infectivity and may play a role in preventing transfusion-transmitted CMV infection in at-risk patients.
Paper Details　
Original Abstract of the Article :
Primary cytomegalovirus (CMV) infection is usually asymptomatic in immunocompetent patients but can cause serious life-threatening complications in immunocompromised CMV-seronegative patients, including patients receiving a bone marrow or peripheral blood stem cell transplant, recipients of some sol...See full text at original site
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引用元：
https://doi.org/10.1016/j.tmrv.2005.08.004

データ提供：米国国立医学図書館（NLM）

The Role of Photochemical Treatment with Amotosalen and UV-A Light in the Prevention of Transfusion-Transmitted Cytomegalovirus Infections

Cytomegalovirus (CMV) infection, like a stealthy desert predator, can pose a significant threat to immunocompromised patients. This study, like a vigilant sentinel guarding a precious oasis, investigates the use of photochemical treatment (PCT) with amotosalen and UV-A light to prevent transfusion-transmitted CMV (TT-CMV) infection.

The Potential of PCT for Blood Safety

This research, like a groundbreaking innovation in a long-standing tradition, highlights the potential of PCT to improve blood safety. The authors found that PCT effectively inactivates CMV in platelet concentrates and may play a vital role in reducing the incidence of TT-CMV infection in high-risk patients.

Advancing Blood Safety Practices

This research, like a beacon of hope in a vast and challenging landscape, represents a significant step forward in advancing blood safety practices. The findings provide compelling evidence for the use of PCT as a proactive approach to preventing transfusion-transmitted infections.

Dr. Camel's Conclusion

This research, like a shimmering desert mirage, offers a promising solution to a persistent challenge in blood safety. The findings underscore the importance of continued innovation in this area, ensuring that patients receive safe and effective blood transfusions. As researchers, we must remain vigilant in our pursuit of safer and more effective treatments, just as the camel tirelessly navigates the desert in search of water and a path to survival.
Date :
  1. Date Completed 2006-04-20
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

16373187

DOI: Digital Object Identifier

10.1016/j.tmrv.2005.08.004

SNS
PICO Info
in preparation
Languages

English

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