A randomized, double-blind, vehicle-controlled, bilateral comparison trial of bexarotene gel 1% versus vehicle gel in combination with narrowband UVB phototherapy for moderate to severe psoriasis vulgaris.

Author: ChristiansenLinda, DombrovskiyViktor, GottliebAlice Bendix, MaglioccoMelissa Amy, PandyaKomal, WongYuk

Paper Details 
Original Abstract of the Article :
We report results of a randomized, vehicle-controlled, bilateral comparison pilot study of bexarotene gel 1% with narrowband UVB (NBUVB) phototherapy for moderate to severe psoriasis. In all, 9 patients applied drug or vehicle gel to comparable target lesions up to twice daily for 10 weeks. NBUVB wa...See full text at original site
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引用元:
https://doi.org/10.1016/j.jaad.2005.09.012

データ提供:米国国立医学図書館(NLM)

Bexarotene Gel in Combination with Narrowband UVB Phototherapy for Psoriasis Vulgaris

This research explores the effectiveness of bexarotene gel 1% in combination with narrowband UVB (NBUVB) phototherapy for moderate to severe psoriasis vulgaris. The researchers conducted a randomized, vehicle-controlled, bilateral comparison pilot study. They found that bexarotene gel 1% combined with NBUVB was significantly more effective than placebo combined with NBUVB in improving target lesion scores.

A Combined Approach: Harnessing the Power of Light and Topical Therapy

This study suggests that combining topical therapy with phototherapy can enhance the effectiveness of psoriasis treatment. The findings demonstrate the synergistic effect of bexarotene gel and NBUVB in improving target lesion scores. Think of it like a desert oasis – the cool water of NBUVB provides immediate relief, while the nourishing shade of bexarotene gel promotes long-term healing.

Finding Relief from Psoriasis: A Personalized Approach

Psoriasis is a chronic skin condition that can significantly impact quality of life. This research offers hope for patients with moderate to severe psoriasis, suggesting that bexarotene gel combined with NBUVB can provide effective treatment. The findings emphasize the importance of finding the right treatment strategy for each individual, considering their specific needs and preferences. Just as a camel adapts its travel plan based on the desert conditions, patients with psoriasis must find a personalized approach to manage their condition.

Dr.Camel's Conclusion

This research highlights the potential of bexarotene gel in combination with narrowband UVB phototherapy for the treatment of moderate to severe psoriasis vulgaris. The findings suggest that combining topical therapy with phototherapy can enhance treatment effectiveness, offering a promising approach for patients seeking relief from this challenging skin condition. Just as a camel navigates the harsh desert landscape, patients with psoriasis can find relief and manage their condition through careful consideration of treatment options and a personalized approach to care.

Date :
  1. Date Completed 2006-05-30
  2. Date Revised 2018-12-03
Further Info :

Pubmed ID

16384765

DOI: Digital Object Identifier

10.1016/j.jaad.2005.09.012

Related Literature

SNS
PICO Info
in preparation
Languages

English

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