[Comparative efficacy and safety of contemporary Angiotensin converting enzyme inhibitors moexipril and spirapril in women with postmenopausal metabolic syndrome].

Author: BelousovIu B, DemidovaM A, LeonovaM V, TarasovA V

Paper Details 
Original Abstract of the Article :
Moexipril (7.4-15 mg/day) was given to 34, spirapril (3-6 mg/day) -- to 18 postmenopausal women with hypertension and metabolic syndrome for 16 weeks. Hydrochlorthiazide was added when therapy was not sufficiently effective. Both angiotensin converting enzyme inhibitors had similar hypotensive activ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/16474309

データ提供:米国国立医学図書館(NLM)

Managing Metabolic Syndrome in Postmenopausal Women: The Role of Angiotensin Converting Enzyme Inhibitors

Metabolic syndrome is a cluster of conditions that increase the risk of heart disease, stroke, and type 2 diabetes. Postmenopausal women are particularly susceptible to metabolic syndrome, making effective management crucial for their health and well-being. This study investigates the efficacy and safety of two angiotensin converting enzyme inhibitors (ACEIs), moexipril and spirapril, in treating hypertension and metabolic syndrome in postmenopausal women. The researchers found that both ACEIs effectively lowered blood pressure, improved lipid and carbohydrate metabolism, and reduced elevated leptin levels. They also observed vasoprotective and nephroprotective effects, suggesting the potential of ACEIs in preventing cardiovascular and kidney disease.

ACEIs: A Promising Option for Postmenopausal Women with Metabolic Syndrome

The study's findings suggest that ACEIs, such as moexipril and spirapril, can be effective treatment options for postmenopausal women with metabolic syndrome, offering benefits beyond blood pressure control. These medications can improve lipid and carbohydrate metabolism, reduce elevated leptin levels, and potentially protect against cardiovascular and kidney disease. This information provides valuable insights for healthcare providers in managing metabolic syndrome in this vulnerable population.

Heart Health and Beyond: Managing Metabolic Syndrome in Postmenopausal Women

Managing metabolic syndrome in postmenopausal women is crucial for protecting their heart health and overall well-being. Adopting a healthy lifestyle, including a balanced diet, regular exercise, and stress management, is essential. Working with a healthcare professional to develop a personalized treatment plan, which may include medication, can help effectively manage metabolic syndrome and reduce the risk of complications.

Dr.Camel's Conclusion

Metabolic syndrome can feel like a scorching desert sun, relentlessly increasing the risk of heart disease and other complications. This study provides valuable insights into the role of ACEIs in managing metabolic syndrome in postmenopausal women, offering hope for a healthier and more fulfilling life. By adopting a comprehensive approach, including healthy lifestyle choices and appropriate medication, we can effectively manage this challenging condition and protect our hearts and overall well-being.

Date :
  1. Date Completed 2006-03-28
  2. Date Revised 2017-11-16
Further Info :

Pubmed ID

16474309

DOI: Digital Object Identifier

16474309

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