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Onset and duration of action of formoterol and tiotropium in patients with moderate to severe COPD.

Author: HarnestUlf, MagnussenHelgo, MückeMarion, RichterKai, SchmidtmannSören, SiederChristian, StengleinStephan, WeidingerGottfried

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Formoterol has faster onset of action and greater bronchodilation than tiotropium in patients with moderate to severe COPD.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Chronic obstructive pulmonary disease (COPD) management guidelines recommend regular treatment with one or more long-acting bronchodilators for patients with moderate to severe COPD. OBJECTIVE: To compare the onset and duration of action of formoterol and tiotropium in patients with COP...See full text at original site
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引用元：
https://doi.org/10.1159/000091996

データ提供：米国国立医学図書館（NLM）

Formoterol and Tiotropium: Comparing Onset and Duration of Action in COPD

This study compares the onset and duration of action of two long-acting bronchodilators, formoterol and tiotropium, in patients with Chronic Obstructive Pulmonary Disease (COPD). The researchers conducted a randomized, crossover study involving patients with moderate to severe COPD, measuring lung function after treatment with each medication. The study found that formoterol had a faster onset of action and greater bronchodilation within the first two hours after inhalation compared to tiotropium. However, both medications showed similar bronchodilation 12 hours after inhalation. This study provides valuable insights into the relative efficacy of these two long-acting bronchodilators for managing COPD.

Formoterol and Tiotropium: Choosing the Right Bronchodilator

This study provides valuable information for healthcare professionals and patients in choosing the most appropriate long-acting bronchodilator for COPD management. The study's findings highlight the different characteristics of formoterol and tiotropium, suggesting that formoterol may be a better choice for patients who require faster relief of symptoms, while tiotropium may be more suitable for maintaining long-term bronchodilation.

COPD: A Camel's Perspective on Lung Function

As a camel, I know that navigating dusty environments requires efficient breathing. COPD, like a sandstorm, can make breathing a challenge. This study helps us understand the nuances of different bronchodilators, offering valuable information for patients and healthcare providers in managing this condition.

Dr.Camel's Conclusion

This study provides valuable insights into the onset and duration of action of formoterol and tiotropium in patients with COPD. The findings suggest that formoterol may be a better choice for patients who require faster relief of symptoms, while tiotropium may be more suitable for maintaining long-term bronchodilation.
Date :
  1. Date Completed 2006-11-14
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

16534180

DOI: Digital Object Identifier

10.1159/000091996

SNS
PICO Info
in preparation
Languages

English

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