Hippocampal electrical stimulation in mesial temporal lobe epilepsy.

Author: KubuC S, McLachlanR S, ParrentA, Tellez-ZentenoJ F, WiebeS

Paper Details 
Original Abstract of the Article :
BACKGROUND: Adjustable, reversible therapies are needed for patients with pharmacoresistant epilepsy. Electrical stimulation of the hippocampus has been proposed as a possible treatment for mesial temporal lobe epilepsy (MTLE). METHODS: Four patients with refractory MTLE whose risk to memory contra...See full text at original site
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引用元:
https://doi.org/10.1212/01.wnl.0000209300.49308.8f

データ提供:米国国立医学図書館(NLM)

Hippocampal Stimulation: A New Pathway for Epilepsy Treatment

Mesial temporal lobe epilepsy (MTLE) is a common form of epilepsy that affects the hippocampus, a brain structure vital for memory and learning. This study explores the potential of hippocampal electrical stimulation as a treatment for refractory MTLE, epilepsy that doesn't respond to medication. The researchers evaluated the effectiveness of electrical stimulation in reducing seizures and its impact on memory function, using a controlled, randomized, and blinded study design.

Hippocampal Stimulation: A Potential Treatment for Refractory MTLE

The study found that hippocampal stimulation led to a reduction in seizures in some patients. The researchers observed a median reduction in seizures of 15% among the participants, indicating that this approach may offer some benefit for refractory MTLE. However, the study notes that the effect sizes were smaller than those reported in previous, non-randomized studies, and further research is needed to confirm the efficacy of hippocampal stimulation.

Exploring New Frontiers in Epilepsy Treatment: The Promise of Hippocampal Stimulation

This study, like a camel venturing into unexplored territory, explores a promising new avenue for treating epilepsy. The findings suggest that hippocampal stimulation may be a valuable tool for managing refractory MTLE, but more research is needed to fully understand its long-term efficacy and safety. This study serves as a reminder that the quest for effective epilepsy treatments continues, with exciting new approaches emerging to improve the lives of those living with this complex condition.

Dr. Camel's Conclusion

This study takes a step into the unexplored desert of hippocampal stimulation as a treatment for refractory MTLE. While the results show promise, further research is needed to confirm its effectiveness and to better understand the long-term implications of this approach. It's a journey of discovery, and this study provides valuable insights into a potential new frontier in epilepsy treatment.

Date :
  1. Date Completed 2006-06-28
  2. Date Revised 2017-11-16
Further Info :

Pubmed ID

16554495

DOI: Digital Object Identifier

10.1212/01.wnl.0000209300.49308.8f

Related Literature

SNS
PICO Info
in preparation
Languages

English

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