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Comparison of the effectiveness and side-effects of tolterodine and oxybutynin in children with detrusor instability.

Author: AkgozSemra, BalkanEmin, DogruyolHasan, KilicNizamettin, SenNuri

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Tolterodine and oxybutynin were equally effective in reducing urge urinary incontinence episodes in children with detrusor instability. Tolterodine had significantly fewer side effects, which may improve compliance during long-term treatment.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Treatment with anticholinergic agents is the mainstay of therapy for detrusor instability (DI), a chronic and morbid condition characterized by urge urinary incontinence. The aim of this study is to assess the effectiveness and tolerability of tolterodine and oxybutynin in children with ...See full text at original site
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引用元：
https://doi.org/10.1111/j.1442-2042.2006.01240.x

データ提供：米国国立医学図書館（NLM）

Tolterodine vs. Oxybutynin for Detrusor Instability in Children

The field of pediatric urology is focused on addressing the unique urinary challenges faced by children. This study compares the effectiveness and side-effect profiles of tolterodine and oxybutynin, two commonly used anticholinergic medications, in treating detrusor instability (DI) in children. It aims to provide clinicians with valuable insights for choosing the most appropriate treatment option based on tolerability and efficacy. This research is like a skilled camel caravan traversing the diverse terrain of pediatric urology, seeking to find the best path for treating DI in children.

Tolterodine Offers Better Tolerability for Children with DI

This study reveals that tolterodine is a viable treatment option for children with DI, demonstrating similar efficacy to oxybutynin with significantly fewer side effects. This finding suggests that tolterodine may offer a more tolerable alternative for long-term treatment, potentially enhancing patient compliance. This discovery is like finding a cooler and more refreshing oasis in the desert, offering a more comfortable and sustainable solution for managing DI in children.

Choosing the Right Treatment for Children with DI

This research provides clinicians with valuable insights for choosing the best treatment for children with DI. It highlights the potential of tolterodine as a well-tolerated and effective alternative to oxybutynin, particularly for long-term management. This research is like a compass guiding us through the complex desert of pediatric urinary disorders, offering a roadmap for choosing the best treatment path for children with DI.

Dr. Camel's Conclusion

This research is like a compassionate camel caravan seeking to provide the best possible care for children with DI. It offers a valuable comparison of treatment options, empowering clinicians to make informed decisions that prioritize both effectiveness and patient comfort.

Date :
  1. Date Completed 2006-08-30
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

16563131

DOI: Digital Object Identifier

10.1111/j.1442-2042.2006.01240.x

Related Literature

Article Analysis
・Side Effects of oxybutynin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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