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Efficacy of a new oral contraceptive containing drospirenone and ethinyl estradiol in the long-term treatment of hirsutism.

Author: BatukanCem, MuderrisIptisam Ipek

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Drospirenone/ethinyl estradiol combination is effective in improving facial hirsutism, with the most significant improvement occurring after six cycles. The combination exerts significant antiandrogenic activity by decreasing serum levels of total and free testosterone and androstenedione, while increasing SHBG levels.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: This study represents long term clinical and biochemical results and the response of different body parts to medical therapy with oral ethinyl estradiol/drospirenone combination in hirsute patients with or without polycystic ovary syndrome (PCOS). DESIGN: Prospective, open, controlled cl...See full text at original site
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引用元：
https://doi.org/10.1016/j.fertnstert.2005.07.1311

データ提供：米国国立医学図書館（NLM）

Tackling Hirsutism: A Camel's Guide to the Desert of Hormonal Balance

Hirsutism, a condition characterized by excessive hair growth in women, can significantly impact self-esteem and quality of life. This study investigates the long-term effectiveness of a new oral contraceptive containing drospirenone and ethinyl estradiol in treating hirsutism, particularly in women with polycystic ovary syndrome (PCOS). The researchers conducted a prospective clinical study involving 50 women with moderate to severe hirsutism, assessing the impact of this medication on hirsutism severity, serum hormone levels, and overall clinical outcomes. The study provides valuable insights into the potential of this oral contraceptive as a therapeutic option for hirsutism.

Drospirenone/Ethinyl Estradiol: A Oasis in the Desert of Hirsutism

The study demonstrates that the combination of drospirenone and ethinyl estradiol significantly reduces hirsutism severity, with the most prominent improvements observed in the chest, abdomen, upper lip, and chin. This finding highlights the effectiveness of this oral contraceptive in targeting the hormonal imbalances underlying hirsutism.

Navigating Hormonal Harmony: A Camel's Perspective on Hirsutism Treatment

The study provides evidence that drospirenone/ethinyl estradiol can be a valuable tool in managing hirsutism, particularly for women with PCOS. The combination of antiandrogenic activity and efficacy in improving facial hirsutism makes this oral contraceptive a promising treatment option. However, it is important to note that individual responses may vary, and a personalized approach to treatment is essential.

Dr. Camel's Conclusion

This research offers a glimmer of hope for women struggling with hirsutism, presenting drospirenone/ethinyl estradiol as a potentially effective treatment option. The study's findings provide valuable insights into the hormonal mechanisms underlying hirsutism and highlight the potential of this oral contraceptive to restore balance and improve quality of life for affected individuals.

Date :
  1. Date Completed 2006-05-08
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

16595223

DOI: Digital Object Identifier

10.1016/j.fertnstert.2005.07.1311

Related Literature

Article Analysis
・Effective treatment of polycystic ovary syndrome
SNS
PICO Info
in preparation
Languages

English

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