Paper Details

  1. Home
  2. Paper Details

Effects of conjugated equine estrogens on breast cancer and mammography screening in postmenopausal women with hysterectomy.

Author: , AndersonGarnet L, AssafAnnlouise R, ChlebowskiRowan T, HendrixSusan L, HubbellF Allan, LaneDorothy S, LessinLawrence, MargolisKaren L, PaskettElectra D, RodaboughRebecca J, SartoGloria E, SchenkenRobert S, StefanickMarcia L, YasmeenShagufta

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

The Women's Health Initiative Estrogen-Alone trial found that conjugated equine estrogens (CEE) increased stroke incidence and did not reduce coronary heart disease risk. However, preliminary results suggest a possible reduction in breast cancers.
Paper Details　
Original Abstract of the Article :
The Women's Health Initiative Estrogen-Aone trial comparing conjugated equine estrogens (CEE) with placebo was stopped early because of an increased stroke incidence and no reduction in risk of coronary heart disease. Preliminary results suggesting possible reduction in breast cancers warranted more...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1001/jama.295.14.1647

データ提供：米国国立医学図書館（NLM）

Conjugated Equine Estrogens: Effects on Breast Cancer and Mammography

The vast desert of women's health research is constantly evolving, with researchers seeking to understand the complex interplay of factors that influence breast cancer risk. This study examines the effects of conjugated equine estrogens (CEE) on breast cancer and mammography screening in postmenopausal women with hysterectomy. The study explores the potential benefits and risks of CEE, a type of hormone replacement therapy, and its impact on breast cancer development.

CEE and Breast Cancer: Navigating the Desert of Uncertainty

The study, which was part of the Women's Health Initiative Estrogen-Aone trial, reveals a complex picture regarding the effects of CEE on breast cancer. While CEE initially showed a possible reduction in breast cancer risk, further analysis revealed no conclusive evidence to support this finding. This research underscores the need for ongoing research to better understand the long-term effects of CEE on breast health and to develop more targeted and effective treatment strategies for women.

Understanding the Landscape of Breast Cancer Risk

This study provides valuable information for women seeking to manage their breast cancer risk. While the findings suggest that CEE may not offer a significant protective benefit, it's important to consult with a healthcare professional for personalized advice. Remember, just as a desert traveler needs a reliable guide, understanding the nuances of breast cancer risk requires a trusted healthcare partner.

Dr. Camel's Conclusion

This research sheds light on the desert landscape of breast cancer risk, offering a glimpse into the complex relationship between CEE and breast health. The findings emphasize the need for continued research to better understand the long-term effects of CEE and to develop more personalized and effective strategies for managing breast cancer risk in women. It's crucial to approach this topic with a discerning eye, seeking guidance from healthcare professionals and staying informed about the latest findings.

Date :
  1. Date Completed 2006-04-14
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

16609086

DOI: Digital Object Identifier

10.1001/jama.295.14.1647

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.