Intraarticular corticosteroid for treatment of osteoarthritis of the knee.

Author: BellamyN, BourneR, CampbellJ, GeeT, RobinsonV, WellsG

Paper Details 
Original Abstract of the Article :
BACKGROUND: Osteoarthritis (OA) is a common joint disorder. In the knee, injections of corticosteroids into the joint (intraarticular (IA)) may relieve inflammation, and reduce pain and disability. OBJECTIVES: To evaluate the efficacy and safety of IA corticosteroids in treatment of OA of the knee....See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1002/14651858.CD005328.pub2

データ提供:米国国立医学図書館(NLM)

Intraarticular Corticosteroids for Osteoarthritis of the Knee

This study investigates the efficacy and safety of intraarticular (IA) corticosteroids for treating osteoarthritis (OA) of the knee, a common joint condition that can significantly affect mobility and quality of life. Researchers analyzed the results of 28 randomized controlled trials to assess the short-term and long-term benefits of IA corticosteroids compared to placebo, other treatments, and even different types of corticosteroids.

Short-Term Relief for Osteoarthritis Pain

The study shows that IA corticosteroids provide short-term pain relief for patients with OA of the knee. The effect is noticeable within a week of injection, with a significant reduction in pain and improvement in patient-reported global assessments. However, the study notes that these benefits are less durable over time. It's like a temporary oasis in the desert, providing respite from pain but not lasting relief.

Long-Term Management: Hyaluronan Products Show Promise

The study suggests that while IA corticosteroids offer temporary relief, hyaluronan (HA) products may provide longer-lasting benefits. HA products are a different type of injection that lubricates and protects the joint. While HA products may have a slower onset of effect, they appear to maintain their effectiveness for a longer duration than corticosteroids. It's like choosing a sturdy camel for a long journey through the desert, HA products offer a more sustainable solution for OA pain compared to the temporary relief of corticosteroids.

Dr.Camel's Conclusion

This study provides valuable insights into the use of IA corticosteroids for OA of the knee. While they offer short-term pain relief, their effects are less durable over time. Further research is needed to investigate the long-term effects of different types of corticosteroids and to explore alternative therapies for OA management. Remember, just like a desert traveler must plan for the long journey, it's important to consider a holistic approach to OA management to ensure long-term well-being.

Date :
  1. Date Completed 2006-06-15
  2. Date Revised 2023-10-24
Further Info :

Pubmed ID

16625636

DOI: Digital Object Identifier

10.1002/14651858.CD005328.pub2

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.