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Therapies for dactylitis in psoriatic arthritis. A systematic review.

Author: HelliwellPhilip S

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Dactylitis, or inflammation of the fingers and toes, is a key feature of psoriatic arthritis (PsA). This review found that dactylitis is linked to the severity of PsA and psoriasis. While traditional treatments include anti-inflammatory drugs and steroid injections, there is limited research on dactylitis treatment, and the need for better ways to measure its improvement. Infliximab is the only drug that has shown significant improvement in dactylitis in a clinical study.
Paper Details　
Original Abstract of the Article :
Dactylitis is a hallmark clinical feature of psoriatic arthritis (PsA). Acute dactylitis appears to be a severity marker for PsA and psoriasis. Traditionally, clinicians have used nonsteroidal antiinflammatory rheumatic drugs and local corticosteroid injections to treat dactylitis, although conventi...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/16724369

データ提供：米国国立医学図書館（NLM）

Dactylitis in Psoriatic Arthritis: A Need for Effective Treatments

Psoriatic arthritis (PsA) is a chronic inflammatory disease characterized by joint pain and swelling, often accompanied by dactylitis, a painful inflammation of the fingers and toes. This systematic review examines the limited data on treatments for dactylitis in PsA, highlighting the need for effective therapeutic approaches.

Limited Data on Dactylitis Treatments

The review found limited evidence on the effectiveness of various treatments for dactylitis in PsA. While traditional treatments like nonsteroidal antiinflammatory drugs and corticosteroid injections are often used, the review suggests that infliximab is the only drug showing significant improvement in dactylitis during clinical studies. This highlights the need for further research to identify effective and safe treatments for dactylitis in PsA.

Improving Dactylitis Treatment in Psoriatic Arthritis

This research underscores the importance of developing more effective treatments for dactylitis in PsA. The lack of robust data emphasizes the need for further research, focusing on identifying new drugs and therapeutic approaches that can alleviate the pain and disability associated with dactylitis. This would significantly improve the quality of life for individuals with PsA.

Dr. Camel's Conclusion

The study's findings emphasize the importance of addressing dactylitis in PsA. Just as a camel navigates the desert, we must seek innovative solutions for managing this painful and debilitating condition. Further research is crucial to develop effective therapies for dactylitis in PsA, improving the lives of those affected by this challenging disease.

Date :
  1. Date Completed 2006-11-07
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

16724369

DOI: Digital Object Identifier

06/13/0514

Related Literature

Article Analysis
・Effective treatment of psoriatic arthritis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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