Cost-effectiveness of pneumococcal conjugate vaccine: evidence from the first 5 years of use in the United States incorporating herd effects.

Author: BlackSteven B, CiurylaVincent, FiremanBruce H, RayG Thomas, WhitneyCynthia G

Paper Details 
Original Abstract of the Article :
BACKGROUND: Pneumococcal conjugate vaccine (PCV) has been in routine use in the United States for 5 years. Prior U.S. cost-effectiveness analyses have not taken into account the effect of the vaccine on nonvaccinated persons. METHODS: We revised a previously published model to simulate the effects ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/16732146

データ提供:米国国立医学図書館(NLM)

Cost-Effectiveness of Pneumococcal Conjugate Vaccine: Evidence from the First 5 Years of Use in the United States Incorporating Herd Effects

Pneumococcal conjugate vaccine (PCV) has been a crucial tool in combating pneumococcal infections, a major cause of illness and death worldwide. This study investigates the cost-effectiveness of PCV, incorporating the impact of herd immunity, the protection extended to non-vaccinated individuals due to widespread vaccination. The authors analyzed data from the first 5 years of PCV use in the United States, examining its impact on both vaccinated and non-vaccinated populations.

The study found that PCV was highly cost-effective, especially when accounting for herd effects. The results indicated that PCV averted a significantly larger number of invasive pneumococcal disease (IPD) cases than initially estimated, resulting in substantial cost savings. This underscores the importance of vaccination programs in achieving population-level benefits beyond individual protection.

Pneumococcal Conjugate Vaccine: A Cost-Effective Public Health Intervention

This research strongly supports the value of PCV as a cost-effective public health intervention. The findings demonstrate that PCV not only protects vaccinated individuals but also significantly reduces the burden of pneumococcal disease in the broader population. This highlights the importance of public health initiatives focused on increasing vaccination coverage, as it can lead to substantial health and economic benefits.

The Importance of Vaccination and Herd Immunity

This study underscores the power of vaccination and herd immunity in protecting populations from infectious diseases. PCV's impact on both vaccinated and non-vaccinated individuals highlights the importance of widespread vaccination programs in creating a stronger public health shield against disease. It encourages further research into the cost-effectiveness of other vaccines and the potential for herd immunity to mitigate the spread of various infectious diseases.

Dr. Camel's Conclusion

Vaccination is like a camel caravan navigating a desert, protecting each individual traveler while also creating a collective force against the dangers of the journey. This study reveals the impressive cost-effectiveness of PCV, highlighting the immense power of herd immunity in safeguarding populations against pneumococcal disease. The study encourages continued efforts to expand vaccination programs, like a caravan reaching new oases of health and well-being for everyone.

Date :
  1. Date Completed 2006-07-27
  2. Date Revised 2006-11-15
Further Info :

Pubmed ID

16732146

DOI: Digital Object Identifier

00006454-200606000-00006

Related Literature

SNS
PICO Info
in preparation
Languages

English

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